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Substance Name: Buprenorphine mixture with Naloxone
RN: 352020-56-5
InChIKey: SFNLWIKOKQVFPB-KZCPYJDTSA-N

Note

  • A pharmaceutical preparation that combines buprenorphine, an OPIOID ANALGESIC with naloxone, a NARCOTIC ANTAGONIST to reduce the potential for NARCOTIC DEPENDENCE in the treatment of pain. It may also be used for OPIATE SUBSTITUTION THERAPY.

Molecular Formula

  • C29-H41-N-O4.C19-H21-N-O4

Molecular Weight

  • 795.0238
 

Classification Codes

  • Analgesics
  • Analgesics, Opioid
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Narcotic Antagonists
  • Narcotics
  • Peripheral Nervous System Agents
  • Sensory System Agents
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Names and Synonyms

Name of Substance

  • Buprenorphine mixture with Naloxone

MeSH Heading

  • Buprenorphine, Naloxone Drug Combination

Synonyms

  • Bunavail
  • Buprenorphine / Naloxone
  • Buprenorphine and Naloxone
  • Buprenorphine hydrochloride and naloxone hydrochloride
  • Buprenorphine-Naloxone
  • Buprenorphine-naloxone combination
  • Naloxone-Buprenorphine
  • Suboxone
  • Zubsolv

Registry Numbers

CAS Registry Number

  • 352020-56-5

System Generated Number

  • 0352020565

Structure Descriptors

InChI

1S/C29H41NO4.C19H21NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;2-4,14,17,21,23H,1,5-10H2/t20-,21-,24-,26+,27-,28+,29-;14-,17+,18+,19-/m11/s1

InChIKey

SFNLWIKOKQVFPB-KZCPYJDTSA-N

Smiles

CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4CC7CC7)c56.Oc8ccc9C[C@H]%10N(CC=C)CC[C@@]%11%12[C@@H](Oc8c9%11)C(=O)CC[C@@]%10%12O