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Substance Name: Viloxazine hydrochloride [USAN]
RN: 35604-67-2
UNII: OQW30I1332
InChIKey: HJOCKFVCMLCPTP-UHFFFAOYSA-N
Note
- A morpholine derivative used as an antidepressant. It is similar in action to IMIPRAMINE.
Molecular Formula
- C13-H19-N-O3.Cl-H
Molecular Weight
- 273.758
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Antidepressant
- Drug / Therapeutic Agent
- Human Data
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Names and Synonyms
Name of Substance
- Viloxazine hydrochloride
- Viloxazine hydrochloride [USAN]
Synonyms
- 2-((2-Ethoxyphenoxy)methyl)morpholine hydrochloride
- 2-((o-Ethoxyphenoxy)methyl)morpholine hydrochloride
- 2-(2-Ethoxyphenoxymethyl)-2,3,5,6-tetrahydro-1,4-oxazine hydrochloride
- 2-(2-Ethoxyphenoxymethyl)tetrahydro-1,4-oxazine hydrochloride
- CCRIS 1915
- EINECS 252-638-6
- ICI 58,834
- Morpholine, 2-((2-ethoxyphenoxy)methyl)-, hydrochloride
- UNII-OQW30I1332
- Vicilan
- Viloxacina clorhidrato
- Viloxacina clorhidrato [Spanish]
- Viloxazine HCl
- Viloxazine hydrochloride
- Vivalan
Systematic Names
- 2-((2-Ethoxyphenoxy)methyl)morpholine hydrochloride
- Emovit
- Morpholine, 2-((2-ethoxyphenoxy)methyl)-, hydrochloride
Registry Numbers
CAS Registry Number
- 35604-67-2
FDA UNII
- OQW30I1332
Related Registry Number
- 46817-91-8 (Parent)
System Generated Number
- 0035604672
Molecular Formulas
Molecular Formula
- C13-H19-N-O3.Cl-H
Molecular Formula Fragments
- C13-H19-N-O3
- Cl-H
- COMPONENT
Structure Descriptors
InChI
InChI=1S/C13H19NO3.ClH/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11;/h3-6,11,14H,2,7-10H2,1H3;1HInChIKey
HJOCKFVCMLCPTP-UHFFFAOYSA-NSmiles
Cl.CCOc1ccccc1OCC2CNCCO2Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
human | TDLo | oral | 25mg/kg/6D (25mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | British Medical Journal. Vol. 2, Pg. 96, 1977. |
mouse | LD50 | intraperitoneal | 162mg/kg (162mg/kg) | Farmaco, Edizione Scientifica. Vol. 35, Pg. 812, 1980. | |
mouse | LD50 | intravenous | 60mg/kg (60mg/kg) | Journal of International Medical Research. Vol. 4, Pg. 83, 1976. | |
mouse | LD50 | oral | 480mg/kg (480mg/kg) | Drug Development Research. Vol. 22, Pg. 385, 1991. | |
rat | LD50 | intraperitoneal | 162mg/kg (162mg/kg) | Farmaco, Edizione Scientifica. Vol. 35, Pg. 812, 1980. | |
rat | LD50 | intravenous | 60mg/kg (60mg/kg) | Journal of International Medical Research. Vol. 4, Pg. 83, 1976. | |
rat | LD50 | oral | 2gm/kg (2000mg/kg) | Journal of International Medical Research. Vol. 4, Pg. 83, 1976. | |
women | TDLo | oral | 30mg/kg (30mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: SLEEP | Journal of International Medical Research. Vol. 4, Pg. 83, 1976. |