Important Announcement

X

ChemIDplus is moving to PubChem in December 2022.
Please see the NLM Technical Bulletin article for more information.

Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Oxymorphone hydrochloride [USP]
RN: 357-07-3
UNII: 5Y2EI94NBC
InChIKey: BCGJBQBWUGVESK-KCTCKCTRSA-N

Note

  • An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)

Molecular Formula

  • C17-H19-N-O4.Cl-H

Molecular Weight

  • 337.801
 

Classification Codes

  • Analgesic (Narcotic)
  • Drug / Therapeutic Agent
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Oxymorphone hydrochloride [USP]

Synonyms

  • 4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride
  • 4,5alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride
  • EINECS 206-610-5
  • Numorphan
  • Opana
  • Opana ER
  • Oxymorphinone hydrochloride
  • Oxymorphone HCl
  • Oxymorphone hydrochloride
  • UNII-5Y2EI94NBC

Systematic Names

  • (5alpha)-4,5-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride
  • Morphinan-6-one, 3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-, hydrochloride
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-methyl-, hydrochloride, (5alpha)-

Registry Numbers

CAS Registry Number

  • 357-07-3

FDA UNII

  • 5Y2EI94NBC

Related Registry Number

  • 76-41-5 (Parent)

System Generated Number

  • 0000357073

Molecular Formulas

Molecular Formula

  • C17-H19-N-O4.Cl-H

Molecular Formula Fragments

  • C17-H19-N-O4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C17H19NO4.ClH/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9;/h2-3,12,15,19,21H,4-8H2,1H3;1H/t12-,15+,16+,17-;/m1./s1

InChIKey

BCGJBQBWUGVESK-KCTCKCTRSA-N

Smiles

Cl.CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 301mg/kg (301mg/kg) BEHAVIORAL: ANALGESIA Therapie. Vol. 15, Pg. 1208, 1960.
mouse LD50 intravenous 185mg/kg (185mg/kg) BEHAVIORAL: ANALGESIA Therapie. Vol. 15, Pg. 1208, 1960.
mouse LD50 oral 402mg/kg (402mg/kg) BEHAVIORAL: ANALGESIA Therapie. Vol. 15, Pg. 1208, 1960.
mouse LD50 subcutaneous 285mg/kg (285mg/kg) BEHAVIORAL: ANALGESIA Therapie. Vol. 15, Pg. 1208, 1960.