Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Adenosine-5'-(N-ethylcarboxamide)
RN: 35920-39-9
InChIKey: JADDQZYHOWSFJD-FLNNQWSLSA-N

Note

  • A stable adenosine A1 and A2 receptor agonist. Experimentally, it inhibits cAMP and cGMP phosphodiesterase activity.

Classification Codes

  • Antineoplastic Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Vasodilator Agents

Molecular Formula

  • C12-H16-N6-O4

Molecular Weight

  • 308.2964
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Adenosine-5'-(N-ethylcarboxamide)

MeSH Heading

  • Adenosine-5'-(N-ethylcarboxamide)

Synonyms

  • 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide
  • 5'-N(Sup 6)-Ethylcarboxamidoadenosine
  • 5'-N-Ethylcarboxamidoadenosine
  • Adenosine-5'-(N-ethylcarboxamide)
  • NECA

Systematic Name

  • beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-

Registry Numbers

CAS Registry Number

  • 35920-39-9

Other Registry Numbers

  • 100111-00-0
  • 110282-65-0
  • 74992-42-0
  • 84272-21-9

System Generated Number

  • 0035920399

Structure Descriptors

InChI

1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1

InChIKey

JADDQZYHOWSFJD-FLNNQWSLSA-N

Smiles

CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 500ug/kg (0.5mg/kg)   Journal of Medicinal Chemistry. Vol. 23, Pg. 313, 1980.
mouse LD50 oral 5mg/kg (5mg/kg)   Journal of Medicinal Chemistry. Vol. 23, Pg. 313, 1980.