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Substance Name: Triciribine [INN]
RN: 35943-35-2
UNII: 2421HMY9N6
InChIKey: HOGVTUZUJGHKPL-HTVVRFAVSA-N
Classification Code
- Mutation Data
Molecular Formula
- C13-H16-N6-O4
Molecular Weight
- 320.307
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Names and Synonyms
Name of Substance
- Triciribine
- Triciribine [INN]
Synonyms
- 1,4,5,6,8-Pentaazaacenaphthylene, 3-amino-1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl-
- 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine
- 3-Amino-1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylene
- BRN 1171593
- NSC 154020
- NSC-154020
- Pentaazacentopthylene
- TCN
- Triciribina
- Triciribina [INN-Spanish]
- Triciribine
- Triciribinum
- Triciribinum [INN-Latin]
- Tricyclic nucleoside
- UNII-2421HMY9N6
Systematic Names
- 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl-
- 1,4,5,6,8-Pentaazaacennaphthylen-3-amine, 1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl-
Registry Numbers
CAS Registry Number
- 35943-35-2
FDA UNII
- 2421HMY9N6
System Generated Number
- 0035943352
Structure Descriptors
InChI
InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1InChIKey
HOGVTUZUJGHKPL-HTVVRFAVSA-NSmiles
CN1N=C(N)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 150mg/kg (150mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
mouse | LD50 | subcutaneous | 199mg/kg (199mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, |