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Substance Name: Camazepam [INN]
RN: 36104-80-0
UNII: HZ3XRH03C3
InChIKey: PXBVEXGRHZFEOF-UHFFFAOYSA-N

Note

  • A benzodiazepine used as a minor tranquilizer; it is the dimethyl carbamate salt of temazepam.

Molecular Formula

  • C19-H18-Cl-N3-O3

Molecular Weight

  • 371.8222
 

Classification Codes

Classification Code

  • Drug / Therapeutic Agent

Superlist Classification Code

  • DEA Schedule IV
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Names and Synonyms

Name of Substance

  • Camazepam
  • Camazepam [INN]

Synonyms

  • 3-N,N-Dimethylcarbamoyloxy-7-chloro-5-phenyl-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  • 5-25-02-00244 (Beilstein Handbook Reference)
  • 7-Chloro-1,3-dihydro-3-(N,N-dimethylcarbamoyl)-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
  • 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-1,4-benzodiazepin-2-one dimethylcarbamate
  • Albego
  • Amotril
  • B 5333
  • BRN 0715180
  • Camazepam
  • Camazepamum
  • Camazepamum [INN-Latin]
  • EINECS 252-866-6
  • Nebolan
  • Panevril
  • Paxor
  • SB 5833
  • UNII-HZ3XRH03C3

Systematic Names

  • 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one dimethylcarbamate (ester)
  • Camazepam
  • Carbamic acid, dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl ester

Superlist Names

  • Camazepam
  • DEA No. 2749
  • Limpidon
  • Paxor

Registry Numbers

CAS Registry Number

  • 36104-80-0

FDA UNII

  • HZ3XRH03C3

Other Registry Number

  • 102818-69-9

System Generated Number

  • 0036104800

Structure Descriptors

InChI

1S/C19H18ClN3O3/c1-22(2)19(25)26-17-18(24)23(3)15-10-9-13(20)11-14(15)16(21-17)12-7-5-4-6-8-12/h4-11,17H,1-3H3

InChIKey

PXBVEXGRHZFEOF-UHFFFAOYSA-N

Smiles

c12C(=NC(C(=O)N(c1ccc(c2)Cl)C)OC(=O)N(C)C)c1ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 800mg/kg (800mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 2032, 1974.
mouse LD50 oral 970mg/kg (970mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 2032, 1974.
rat LD50 oral > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 2029, 1974.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 173.5 deg C   EXP
log P (octanol-water) 2.660 (none)   EST
Atmospheric OH Rate Constant 2.09E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.