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Substance Name: Latrepirdine [USAN:INN]
RN: 3613-73-8
UNII: OD9237K1Z6
InChIKey: JNODQFNWMXFMEV-UHFFFAOYSA-N

Classification Codes

  • Reproductive Effect
  • Treatment of Alzheimer's Disease

Molecular Formula

  • C21-H25-N3

Molecular Weight

  • 319.4495
 
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Names and Synonyms

Name of Substance

  • Latrepirdine
  • Latrepirdine [USAN:INN]

Synonyms

  • 2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole
  • 5-23-07-00382 (Beilstein Handbook Reference)
  • BRN 0622478
  • Dimebolin
  • Dimeboline
  • Dimebon
  • Dimebone
  • Latrepirdine
  • Preparation 84
  • UNII-OD9237K1Z6

Systematic Name

  • 1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-

Registry Numbers

CAS Registry Number

  • 3613-73-8

FDA UNII

  • OD9237K1Z6

Other Registry Numbers

  • 12687-54-6
  • 20684-30-4

System Generated Number

  • 0003613738

Structure Descriptors

InChI

1S/C21H25N3/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17/h4-7,12-13H,8-11,14H2,1-3H3

InChIKey

JNODQFNWMXFMEV-UHFFFAOYSA-N

Smiles

n1(c2c(c3cc(ccc13)C)CN(CC2)C)CCc1cnc(cc1)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 178mg/kg (178mg/kg)   Russian Pharmacology and Toxicology Vol. 31, Pg. 105, 1968.
mouse LDLo oral 356mg/kg (356mg/kg)   Farmakologiya i Toksikologiya Vol. 46(5), Pg. 90, 1983.