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Substance Name: Tramadol hydrochloride [USAN:USP:JAN]
RN: 36282-47-0
UNII: 9N7R477WCK
InChIKey: PPKXEPBICJTCRU-XMZRARIVSA-N

Note

  • A narcotic analgesic proposed for severe pain. It may be habituating.

Classification Code

  • Analgesic

Molecular Formula

  • C16-H25-N-O2.Cl-H

Molecular Weight

  • 299.8394
 

Names and Synonyms

Name of Substance

  • Tramadol hydrochloride
  • Tramadol hydrochloride [USAN:USP:JAN]

Synonyms

  • (+-)-cis-2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
  • (+-)-cis-2-((Dimethylamino)methyl)-1-(m-methoxyphenyl)cyclohexanol hydrochloride
  • Adamon
  • Adolanta
  • Amadol
  • Bellatram
  • Cemadol
  • CG 315
  • CG-315E
  • cis-Tramadol hydrochloride
  • Contramal
  • Conzip
  • Crispin
  • Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, cis-
  • Dolana
  • EINECS 252-950-2
  • Ira-Tramadol
  • Mabron
  • Melanate
  • NIH 10969
  • Omnidol
  • Poltram
  • Radol
  • Rybix
  • Rybix ODT
  • Ryzolt
  • Synapryn
  • Tadol
  • Topalgic
  • Trabar
  • Tradol-Puren
  • Tradonal
  • Tramadex
  • Tramadol HCl
  • Tramadol hydrochloride
  • Tramagetic
  • Tramal
  • Tramal Retard
  • Tramazac
  • Tramed
  • Tramol
  • Tramundin
  • Tridol
  • Tridural
  • U-26,225A
  • Ultram
  • Ultram ER
  • UNII-9N7R477WCK
  • Viotra
  • Zumatran
  • Zydol
  • Zydol XL 150

Systematic Names

  • Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, (1R,2R)-rel-
  • Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, cis-(+-)-

Registry Numbers

CAS Registry Number

  • 36282-47-0

FDA UNII

  • 9N7R477WCK

Other Registry Numbers

  • 194602-08-9
  • 22204-88-2
  • 53611-16-8

System Generated Number

  • 0036282470

Molecular Formulas

Molecular Formula

  • C16-H25-N-O2.Cl-H

Molecular Formula Fragments

  • C16-H25-N-O2
  • Cl-H

Structure Descriptors

InChI

1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1

InChIKey

PPKXEPBICJTCRU-XMZRARIVSA-N

Smiles

CN(C)C[C@H]1CCCC[C@@]1(c2cccc(c2)OC)O.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 61700ug/kg (61.7mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 114, 1978.
mouse LD50 subcutaneous 224mg/kg (224mg/kg) BEHAVIORAL: ANALGESIA Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 114, 1978.