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Substance Name: Tricetamide [USAN]
RN: 363-20-2
UNII: V6X0RFU7AF
InChIKey: NLRFFZRHTICQBO-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Sedative
  • Sedative-Hypnotic

Molecular Formula

  • C16-H24-N2-O5

Molecular Weight

  • 324.375
 
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Names and Synonyms

Name of Substance

  • Tricetamide [USAN]

Synonyms

  • 4-10-00-02022 (Beilstein Handbook Reference)
  • Benzamide, N-(2-(diethylamino)-2-oxoethyl)-3,4,5-trimethoxy-
  • BRN 2708816
  • N-((Diethylcarbamoyl)methyl)-3,4,5-trimethoxybenzamide
  • N-(3,4,5-Trimethoxybenzoyl)glycine diethylamide
  • N-3,4,5-Trimethoxybenzoylglycin-diethylamid
  • R-548
  • Riker 548
  • Tricetamide
  • Trimeglamide
  • Trimethobenzglycin
  • UNII-V6X0RFU7AF

Systematic Names

  • Benzamide, N-((diethylcarbamoyl)methyl)-3,4,5-trimethoxy-
  • Benzamide, N-(2-(diethylamino)-2-oxoethyl)-3,4,5-trimethoxy-

Registry Numbers

CAS Registry Number

  • 363-20-2

FDA UNII

  • V6X0RFU7AF

System Generated Number

  • 0000363202

Structure Descriptors

InChI

1S/C16H24N2O5/c1-6-18(7-2)14(19)10-17-16(20)11-8-12(21-3)15(23-5)13(9-11)22-4/h8-9H,6-7,10H2,1-5H3,(H,17,20)

InChIKey

NLRFFZRHTICQBO-UHFFFAOYSA-N

Smiles

c1(c(cc(cc1OC)C(NCC(N(CC)CC)=O)=O)OC)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3200mg/kg (3200mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 86, Pg. 120, 1966.
mouse LD50 oral 2400mg/kg (2400mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Pharmazie. Vol. 17, Pg. 351, 1962.
mouse LD50 unreported 3gm/kg (3000mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 380, 1972.
rat LD50 intraperitoneal 340mg/kg (340mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: ATAXIA
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 218, 1962.