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Substance Name: Etidocaine [USAN:INN:BAN]
RN: 36637-18-0
UNII: I6CQM0F31V
InChIKey: VTUSIVBDOCDNHS-UHFFFAOYSA-N

Note

  • A local anesthetic with rapid onset and long action, similar to BUPIVACAINE.

Molecular Formula

  • C17-H28-N2-O

Molecular Weight

  • 276.4212
 

Classification Codes

  • Anesthetic (Local)
  • Anesthetics
  • Anesthetics, Local
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Drug / Therapeutic Agent
  • Peripheral Nervous System Agents
  • Sensory System Agents
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Names and Synonyms

Name of Substance

  • Etidocaine
  • Etidocaine [USAN:INN:BAN]

MeSH Heading

  • Etidocaine

Synonyms

  • (+-)-2-(Ethylpropylamino)-2',6'-butyroxylidide
  • (+-)-N-(2,6-Dimethylphenyl)-2-(ethylpropylamino)butanamide
  • BRN 2741181
  • Duranest
  • EINECS 253-143-8
  • Etidocaina
  • Etidocaina [INN-Spanish]
  • Etidocaine
  • Etidocainum
  • Etidocainum [INN-Latin]
  • UNII-I6CQM0F31V
  • W-19053 [as hydrochloride]

Systematic Names

  • Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, (+-)-
  • Etidocaine

Registry Numbers

CAS Registry Number

  • 36637-18-0

FDA UNII

  • I6CQM0F31V

System Generated Number

  • 0036637180

Structure Descriptors

InChI

1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)

InChIKey

VTUSIVBDOCDNHS-UHFFFAOYSA-N

Smiles

CCCN(CC)C(CC)C(=O)Nc1c(cccc1C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 47500ug/kg (47.5mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 42, Pg. 201, 1990.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 3.69 (none)   EXP
Water Solubility 11.9 mg/L 25 EST
Vapor Pressure 1.47E-07 mm Hg 25 EST
Henry's Law Constant 3.07E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.26E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.