Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Etidocaine hydrochloride
RN: 36637-19-1
UNII: G6N3B3U8E6
InChIKey: LMWQQUMMGGIGJQ-UHFFFAOYSA-N

Note

  • A local anesthetic with rapid onset and long action, similar to BUPIVACAINE.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H28-N2-O.Cl-H

Molecular Weight

  • 312.8821
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Etidocaine hydrochloride

Synonyms

  • (+-)-2-(N-Ethylpropylamino)-2',6'-butyroxylidide hydrochloride
  • Duranest
  • EINECS 253-144-3
  • Etidocaine HCl
  • Etidocaine hydrochloride
  • UNII-G6N3B3U8E6
  • W 19053
  • W-19053

Systematic Names

  • (1)-N-(2,6-Dimethylphenyl)-2-(ethylpropylamino)butyramide monohydrochloride
  • 2',6'-Butyroxylidide, 2-(N-ethylpropylamino)-, hydrochloride, (+-)-
  • Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, monohydrochloride, (+-)- (9CI)

Registry Numbers

CAS Registry Number

  • 36637-19-1

FDA UNII

  • G6N3B3U8E6

System Generated Number

  • 0036637191

Molecular Formulas

Molecular Formula

  • C17-H28-N2-O.Cl-H

Molecular Formula Fragments

  • C17-H28-N2-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H28N2O.ClH/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5;/h9-11,15H,6-8,12H2,1-5H3,(H,18,20);1H

InChIKey

LMWQQUMMGGIGJQ-UHFFFAOYSA-N

Smiles

CCC[NH+](CC)C(CC)C(=O)Nc1c(cccc1C)C.[Cl-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 10mg/kg (10mg/kg)   Toxicology and Applied Pharmacology. Vol. 37, Pg. 13, 1976.
mouse LD50 intramuscular 58178ug/kg (58.178mg/kg)   Drug Development Research. Vol. 21, Pg. 277, 1990.
mouse LD50 intraperitoneal 64400ug/kg (64.4mg/kg) BEHAVIORAL: ANTICONVULSANT

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Anesthesia and Analgesia Vol. 60, Pg. 385, 1981.
mouse LD50 intravenous 6700ug/kg (6.7mg/kg)   Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1829, 1972.
mouse LD50 subcutaneous 99mg/kg (99mg/kg)   Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1829, 1972.