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Substance Name: Lurasidone hydrochloride [USAN]
RN: 367514-88-3
UNII: O0P4I5851I
InChIKey: NEKCRUIRPWNMLK-SCIYSFAVSA-N
Note
- A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.
Molecular Formula
- C28-H36-N4-O2-S.Cl-H
Molecular Weight
- 529.1453
Classification Codes
- Adrenergic Agents
- Adrenergic alpha-2 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Dopamine D2 Receptor Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Serotonin 5-HT2 Receptor Antagonists
- Serotonin Agents
- Serotonin Antagonists
- Tranquilizing Agents
- Treatment of Schizophrenia (High-Affinity Agonist of Serotonin 5-HT1A, 5-HT2, and 5-HT7 Receptors as Well as Dopamine D2 Receptors)
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Names and Synonyms
Name of Substance
- Lurasidone hydrochloride [USAN]
MeSH Heading
- Lurasidone Hydrochloride
Synonyms
- Latuda
- Lurasidone HCl
- Lurasidone hydrochloride
- SM 13496
- SM-13496
- UNII-O0P4I5851I
Systematic Name
- 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-(((1R,2R)-2-((4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)methyl)cyclohexyl)methyl)hexahydro-, monohydrochloride, (3aR,4S,7R,7aS)-
Registry Numbers
CAS Registry Number
- 367514-88-3
FDA UNII
- O0P4I5851I
Other Registry Number
- 441351-20-8
System Generated Number
- 0367514883
Molecular Formulas
Molecular Formula
- C28-H36-N4-O2-S.Cl-H
Molecular Formula Fragments
- C28-H36-N4-O2-S
- Cl-H
- COMPONENT