Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Oxomemazine [INN:DCF]
RN: 3689-50-7
UNII: 305MB38V1C
InChIKey: QTQPVLDZQVPLGV-UHFFFAOYSA-N

Note

  • Selective for M1 muscarinic receptors.

Classification Codes

  • Drug / Therapeutic Agent
  • Skin / Eye Irritant

Molecular Formula

  • C18-H22-N2-O2-S

Molecular Weight

  • 330.4498
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Oxomemazine
  • Oxomemazine [INN:DCF]

Synonyms

  • 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine 5,5-dioxide
  • 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine-5,5-dioxide
  • 4-27-00-01270 (Beilstein Handbook Reference)
  • 6847 R.P.
  • Alimemazine S,S-dioxide
  • BRN 0289178
  • Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine
  • Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine [French]
  • Dosegran
  • Doxergan
  • Dysedon
  • EINECS 222-996-8
  • Imakol
  • Oxomemazina
  • Oxomemazina [INN-Spanish]
  • Oxomemazine
  • Oxomemazinum
  • Oxomemazinum [INN-Latin]
  • Oxymemazine
  • RP 6847
  • UNII-305MB38V1C

Systematic Names

  • 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine 5,5-dioxide
  • Oxomemazine
  • Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-, 5,5-dioxide

Registry Numbers

CAS Registry Number

  • 3689-50-7

FDA UNII

  • 305MB38V1C

System Generated Number

  • 0003689507

Structure Descriptors

InChI

1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3

InChIKey

QTQPVLDZQVPLGV-UHFFFAOYSA-N

Smiles

CC(CN1c2ccccc2S(=O)(=O)c3c1cccc3)CN(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 185mg/kg (185mg/kg) BEHAVIORAL: IRRITABILITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 57, Pg. 460, 1961.
mouse LD50 intravenous 35mg/kg (35mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 364, 1962.
mouse LD50 oral 140mg/kg (140mg/kg)   Therapie. Vol. 26, Pg. 1203, 1971.
mouse LD50 subcutaneous 260mg/kg (260mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 364, 1962.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 115 deg C   EXP
log P (octanol-water) 2.51 (none)   EXP
Water Solubility 46.1 mg/L 25 EST
Vapor Pressure 1.47E-08 mm Hg 25 EST
Henry's Law Constant 5.25E-12 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.56E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.