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Substance Name: Cyclopropylamine, 2-phenyl-, (1S-trans)-
RN: 3721-28-6
InChIKey: AELCINSCMGFISI-DTWKUNHWSA-N

Classification Codes

  • Mutation Data
  • Reproductive Effect

Molecular Formula

  • C9-H11-N

Molecular Weight

  • 133.193
 
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Names and Synonyms

Synonyms

  • (+)-(R)-Tranylcypromine
  • (+)-Tranylcypromine
  • 2-Phenyl-1-aminocyclopropane, trans-
  • BRN 2802413
  • d-Tranylcypromine
  • trans-2-Phenylcyclopropylamine

Systematic Name

  • Cyclopropylamine, 2-phenyl-, (1S-trans)-

Registry Numbers

CAS Registry Number

  • 3721-28-6

System Generated Number

  • 0003721286

Structure Descriptors

InChI

1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m0/s1

InChIKey

AELCINSCMGFISI-DTWKUNHWSA-N

Smiles

c1([C@H]2[C@@H](N)C2)ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 11300ug/kg (11.3mg/kg)   British Patent Document. Vol. #1460700,
mouse LD50 intravenous 37mg/kg (37mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse LD50 oral 20mg/kg (20mg/kg)   Biochemical Pharmacology. Vol. 17, Pg. 369, 1968.
mouse LD50 subcutaneous 30mg/kg (30mg/kg)   Biochemical Pharmacology. Vol. 17, Pg. 369, 1968.
rat LD50 intraperitoneal 30mg/kg (30mg/kg)   Food and Cosmetics Toxicology. Vol. 3, Pg. 597, 1965.
rat LDLo parenteral 100mg/kg (100mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Pharmakopsychiatrie/Neuro-Psychopharmakologie. Vol. 13, Pg. 130, 1980.