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Substance Name: Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination
RN: 37270-71-6
InChIKey: NAPPWIFDUAHTRY-XYDRQXHOSA-N

Note

  • Contains norethindrone & ethinyl estradiol.

Molecular Formula

  • C20-H26-O2.C20-H24-O2

Molecular Weight

  • 594.831
 

Classification Codes

  • Contraceptive Agents
  • Contraceptive Agents, Female
  • Contraceptives, Oral
  • Contraceptives, Oral, Combined
  • Contraceptives, Oral, Hormonal
  • Contraceptives, Oral, Sequential
  • Contraceptives, Oral, Synthetic
  • Drug / Therapeutic Agent
  • Hormone
  • Human Data
  • Mutation Data
  • Reproductive Control Agents
  • Reproductive Effect
  • Tumor Data
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Names and Synonyms

Name of Substance

  • Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination

Synonyms

  • Aranelle
  • Balziva
  • Balziva-21
  • Balziva-28
  • Binovum
  • Brevicon
  • Brevicon 21-day
  • Brevicon 28-day
  • Cyclafem 1/35
  • Cyclafem 7/7/7
  • Cyonanz
  • DT 5061
  • DT 5062
  • DT-5062(1/35)
  • Duagynon
  • E-Con
  • Ethinylestradiol-norethisterone mixt.
  • Ethynyl estradiol / norethindrone
  • Ethynylestradiol / norethindrone
  • Ethynylestradiol mixed with norethindrone
  • Ethynylestradiol mixture with norethindrone
  • Eve 20
  • Femcon Fe
  • Gencept 10/11-21
  • Gencept 10/11-28
  • Gynovlar
  • Kaitlib Fe
  • Lo Minastrin Fe
  • Modicon
  • Modicon 21
  • Modicon 28
  • N.E.E. 1/35 21
  • N.E.E. 1/35 28
  • Necon 7/7/7 28-Day Tablets
  • Neocon
  • Netasyn
  • Norcept-E 1/35 21
  • Norcept-E 1/35 28
  • Norethin 1/35e-21
  • Norethin 1/35e-28
  • Norethindron-ethinylestradiol mixt.
  • Norethindrone and ethinyl estradiol
  • Norethindrone and ethinyl estradiol (10/11)
  • Norethindrone and ethinyl estradiol (7/14)
  • Norethindrone Ethinyl Estradiol
  • Norethindrone mixed with ethynylestradiol
  • Norethindrone mixture with ethinyl estradiol
  • Norethindrone-ethinylestradiol mixt.
  • Norethisterone mixed with ethinyl oestradiol
  • Norethisterone-ethinylestradiol mixt.
  • Norethisterone-ethynylestradiol mixt.
  • Norimin
  • Norinyl 1 35
  • Norinyl 1+35 21-day
  • Norinyl 1+35 28-day
  • Norminest
  • Nortrel 0.5/35-21
  • Nortrel 0.5/35-28
  • Nortrel 1/35-21
  • Nortrel 1/35-28
  • Nortrel 7/7/7
  • Nylia 1/35
  • Nylia 7/7/7
  • Oestro-primolut
  • Ortho-Novum 1/35
  • Ortho-Novum 1/35-21
  • Ortho-Novum 1/35-28
  • Ortho-novum 10/11
  • Ortho-Novum 10/11-21
  • Ortho-Novum 10/11-28
  • Ortho-Novum 7/14-21
  • Ortho-Novum 7/14-28
  • Ortho-novum 7/7/7
  • Ortho-Novum 7/7/7-21
  • Ortho-Novum 7/7/7-28
  • Ortho-Novum 777
  • Ovcon
  • Ovcon 35
  • Ovcon 50
  • Ovcon-35
  • Ovcon-50
  • Ovysmen
  • Tri-Norinyl 21-day
  • Tri-Norinyl 28-day
  • Trinovum
  • Zenchent

Systematic Names

  • (17alpha)-17-Hydroxy-19-norpregn-4-en-20-yn-3-one, mixture with (17alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol
  • 19-Nor-17-alpha-pregn-4-en-20-yn-3-one, 17-hydroxy-, mixed with 19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yne-3,17-diol

Registry Numbers

CAS Registry Number

  • 37270-71-6

Other Registry Number

  • 53464-69-0

System Generated Number

  • 0037270716

Molecular Formulas

Molecular Formula

  • C20-H26-O2.C20-H24-O2

Molecular Formula Fragments

  • C20-H24-O2
  • C20-H26-O2
  • COMPONENT

Structure Descriptors

InChI

1S/C20H26O2.C20H24O2/c2*1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3;1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t15-,16+,17+,18-,19-,20-;16-,17-,18+,19+,20+/m01/s1

InChIKey

NAPPWIFDUAHTRY-XYDRQXHOSA-N

Smiles

C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@]2(C#C)O)O.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 2gm/kg (2000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl,
mouse LD50 oral > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl,
rat LD50 oral > 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl,
women TDLo oral 55mg/kg/5Y-I (55mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Lancet. Vol. 1, Pg. 1479, 1973.