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Substance Name: Serrapeptase [INN:DCF:JAN]
RN: 37312-62-2

Note

  • Proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Drug / Therapeutic Agent
  • Peripheral Nervous System Agents
  • Sensory System Agents
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Links to Resources

Names and Synonyms

Name of Substance

  • Serrapeptase [INN:DCF:JAN]

Synonyms

  • Aniflazime
  • Brasan
  • Dasen
  • EINECS 253-457-5
  • Peptizyme SP
  • Serrapeptasa
  • Serrapeptasa [INN-Spanish]
  • Serrapeptase
  • Serrapeptasum
  • Serrapeptasum [INN-Latin]
  • Serratia extracellular proteinase
  • Serratio peptidase
  • Serratiopeptidase

Systematic Names

  • A proteolytic enzyme derived from Serratia sp.E15
  • Proteinase, Serratia extracellular

Registry Numbers

CAS Registry Number

  • 37312-62-2

System Generated Number

  • 0037312622

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 15200ug/kg (15.2mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
mouse LD50 intravenous 14230ug/kg (14.23mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
mouse LD50 oral > 2500mg/kg (2500mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
mouse LD50 subcutaneous 44mg/kg (44mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
rat LD50 intraperitoneal 34620ug/kg (34.62mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
rat LD50 intravenous 6950ug/kg (6.95mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
rat LD50 oral > 2500mg/kg (2500mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.
rat LD50 subcutaneous 89mg/kg (89mg/kg)   Drugs in Japan Vol. 6, Pg. 415, 1982.