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Substance Name: Decloxizine [INN]
RN: 3733-63-9
UNII: 919C49XAYD
InChIKey: OXBBIHZWNDPBMQ-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C21-H28-N2-O2

Molecular Weight

  • 340.4642
 
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Names and Synonyms

Name of Substance

  • Decloxazine
  • Decloxizine [INN]

Synonyms

  • 1-(Diphenylmethyl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine
  • 1-Benzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine
  • 2-(2-((4-Diphenylmethyl)-1-piperazinyl)ethoxy)ethanol
  • 2-(2-(4-Benzhydryl-1-piperazinyl)ethoxy)ethanol
  • 2-{2-(4-(Diphenylmethyl)-1-piperazinyl)ethoxy}ethanol
  • 4-23-00-00103 (Beilstein Handbook Reference)
  • BRN 0306385
  • Decloxizina
  • Decloxizina [INN-Spanish]
  • Decloxizine
  • Decloxizinum
  • Decloxizinum [INN-Latin]
  • Hydroxydiethylphenamine
  • NSC 289116
  • UCB 1402
  • UNII-919C49XAYD

Systematic Names

  • 2-2-(4-(Diphenylmethyl)-1-piperazinyl)ethoxyethanol
  • Ethanol, 2-(2-(4-(diphenylmethyl)-1-piperazinyl)ethoxy)-

Registry Numbers

CAS Registry Number

  • 3733-63-9

FDA UNII

  • 919C49XAYD

Related Registry Number

  • 13073-96-6 (di-hydrochloride)

System Generated Number

  • 0003733639

Structure Descriptors

InChI

1S/C21H28N2O2/c24-16-18-25-17-15-22-11-13-23(14-12-22)21(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-10,21,24H,11-18H2

InChIKey

OXBBIHZWNDPBMQ-UHFFFAOYSA-N

Smiles

c1ccc(cc1)C(c2ccccc2)N3CCN(CC3)CCOCCO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 135mg/kg (135mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1002, 1968.
mouse LD50 intravenous 45mg/kg (45mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1002, 1968.
mouse LD50 oral 470mg/kg (470mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1002, 1968.
rat LD50 intraperitoneal 103mg/kg (103mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1002, 1968.
rat LD50 intravenous 47mg/kg (47mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1002, 1968.
rat LD50 oral 840mg/kg (840mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1002, 1968.