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Substance Name: Amylase, phosphates, proteases drug combinations
RN: 37338-91-3

Note

  • Russian preparation with thrombolytic properties; contains proteases, phosphates, & amylase; from cultures of Asp. terricola.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Adjuvants, Immunologic
  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Cardiovascular Agents
  • Coagulants
  • Fibrin Modulating Agents
  • Fibrinolytic Agents
  • Hematologic Agents
  • Hemostatics
  • Immunologic Factors
  • Natural Product
  • Peripheral Nervous System Agents
  • Sensory System Agents
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Names and Synonyms

Name of Substance

  • Amylase, phosphates, proteases drug combinations

Synonyms

  • Terrilitin
  • Terrilytin

Systematic Name

  • Proteinase, aspergillus terricola neutral

Registry Numbers

CAS Registry Number

  • 37338-91-3

System Generated Number

  • 0037338913

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 10mg/kg (10mg/kg) KIDNEY, URETER, AND BLADDER: HEMATURIA

GASTROINTESTINAL: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.
mouse LD50 intramuscular 208mg/kg (208mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.
mouse LD50 intraperitoneal 98ug/kg (0.098mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.
mouse LD50 intravenous 12500ug/kg (12.5mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.
mouse LD50 oral 7500mg/kg (7500mg/kg)   Pharmaceutical Chemistry Journal Vol. 10, Pg. 1130, 1976.
mouse LD50 subcutaneous 220mg/kg (220mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.
rabbit LD50 intravenous 50mg/kg (50mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.
rat LD50 intravenous 91700ug/kg (91.7mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Farmakologiya i Toksikologiya Vol. 37, Pg. 608, 1974.