Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Phoratoxin protein, Phoradendron tomentosum
RN: 37339-68-7
InChIKey: LNSFJMHTXNGFBR-SUBMMNEBSA-N

Note

  • Small basic protein (46 amino acids) from mistletoe Phoradendron tomentosum subsp. macrophyllum (Loranthaceae); has toxic properties.

Molecular Formula

  • C203-H329-N65-O63-S6

Molecular Weight

  • 4874.5727
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Phoratoxin protein, Phoradendron tomentosum

Synonyms

  • Phoratoxin
  • Phoratoxin B protein, Phoradendron tomentosum

Systematic Names

  • L-Histidine, L-lysyl-L-seryl-L-cysteinyl-L-cysteinyl-L-prolyl-L-threonyl-L-threonyl-L-alanyl-L-arginyl-L-asparaginyl-L-isoleucyl-L-tyrosyl-L-asparaginyl-L-threonyl-L-cysteinyl-L-arginyl-L-phenylalanylglycylglycylglycyl-L-seryl-L-arginyl-L-prolyl-L-valyl-L-cysteinyl-L-alanyl-L-lysyl-L-leucyl-L-serylglycyl-L-cysteinyl-L-lysyl-L-isoleucyl-L-isoleucyl-L-serylglycyl-L-threonyl-L-lysyl-L-cysteinyl-L-alpha-aspartyl-L-serylglycyl-L-tryptophyl-L-asparaginyl-
  • Phoratoxin A (reduced) (9CI)

Registry Numbers

CAS Registry Number

  • 37339-68-7

System Generated Number

  • 0037339687

Structure Descriptors

InChI

1S/C203H323N65O63S6/c1-18-96(8)153-190(320)247-122(67-107-52-54-110(279)55-53-107)174(304)245-126(72-144(211)282)179(309)263-158(103(15)276)195(325)256-138-91-336-333-88-135(255-189(319)152(95(6)7)259-187(317)140-50-37-63-267(140)198(328)119(49-36-62-221-203(216)217)240-180(310)132(85-272)233-147(285)78-224-145(283)76-223-146(284)77-225-164(294)121(66-106-39-22-21-23-40-106)242-170(300)118(238-184(138)314)48-35-61-220-202(214)215)182(312)230-99(11)161(291)235-114(44-27-31-57-205)168(298)241-120(65-94(4)5)173(303)250-129(82-269)165(295)227-80-149(287)234-134-87-332-337-92-139(199(329)268-64-38-51-141(268)188(318)264-159(104(16)277)196(326)266-160(105(17)278)197(327)265-157(102(14)275)193(323)231-100(12)162(292)236-117(47-34-60-219-201(212)213)169(299)243-125(71-143(210)281)178(308)261-153)257-186(316)137(254-181(311)133(86-273)249-163(293)112(208)42-26-30-56-204)90-335-334-89-136(253-171(301)115(45-28-32-58-206)239-194(324)156(101(13)274)258-150(288)81-228-167(297)131(84-271)252-191(321)154(97(9)19-2)262-192(322)155(98(10)20-3)260-172(302)116(237-183(134)313)46-29-33-59-207)185(315)246-127(73-151(289)290)177(307)251-130(83-270)166(296)226-79-148(286)232-123(68-108-74-222-113-43-25-24-41-111(108)113)175(305)244-124(70-142(209)280)176(306)248-128(200(330)331)69-109-75-218-93-229-109/h21-25,39-41,43,52-55,74-75,93-105,112,114-141,152-160,222,269-279H,18-20,26-38,42,44-51,56-73,76-92,204-208H2,1-17H3,(H2,209,280)(H2,210,281)(H2,211,282)(H,218,229)(H,223,284)(H,224,283)(H,225,294)(H,226,296)(H,227,295)(H,228,297)(H,230,312)(H,231,323)(H,232,286)(H,233,285)(H,234,287)(H,235,291)(H,236,292)(H,237,313)(H,238,314)(H,239,324)(H,240,310)(H,241,298)(H,242,300)(H,243,299)(H,244,305)(H,245,304)(H,246,315)(H,247,320)(H,248,306)(H,249,293)(H,250,303)(H,251,307)(H,252,321)(H,253,301)(H,254,311)(H,255,319)(H,256,325)(H,257,316)(H,258,288)(H,259,317)(H,260,302)(H,261,308)(H,262,322)(H,263,309)(H,264,318)(H,265,327)(H,266,326)(H,289,290)(H,330,331)(H4,212,213,219)(H4,214,215,220)(H4,216,217,221)/t96-,97-,98-,99-,100-,101+,102+,103+,104+,105+,112-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,152-,153-,154-,155-,156-,157-,158-,159-,160-/m0/s1

InChIKey

LNSFJMHTXNGFBR-SUBMMNEBSA-N

Smiles

CC[C@H](C)[C@@H]1NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CSSC[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]4CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](Cc5ccc(O)cc5)NC1=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc6ccccc6)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N7CCC[C@H]7C(=O)N[C@@H](C(C)C)C(=O)N4)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N3)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](Cc8c[nH]c9ccccc89)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc%10cnc[nH]%10)C(=O)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 1mg/kg (1mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

CARDIAC: CHANGE IN RATE
Toxicon. Vol. 4, Pg. 107, 1966.