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Substance Name: JNJ-10258859
RN: 374927-03-4
UNII: 4NPX9224XR
InChIKey: MVMQGWXVSBNFLB-MUUNZHRXSA-N

Note

  • Potent and selective phosphodiesterase type 5 inhibitor.

Molecular Formula

  • C30-H24-N4-O3

Molecular Weight

  • 488.5446
 
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Names and Synonyms

Name of Substance

  • JNJ-10258859

Synonyms

  • 9H-Pyrrolo(3,4-b)quinolin-9-one, 3-(2,3-dihydro-5-benzofuranyl)-1,2,3,4-tetrahydro-2-(5-(4-methoxyphenyl)-2-pyrimidinyl)-, (3R)-
  • JNJ-10258859
  • UNII-4NPX9224XR

Registry Numbers

CAS Registry Number

  • 374927-03-4

FDA UNII

  • 4NPX9224XR

System Generated Number

  • 0374927034

Structure Descriptors

InChI

1S/C30H24N4O3/c1-36-22-9-6-18(7-10-22)21-15-31-30(32-16-21)34-17-24-27(33-25-5-3-2-4-23(25)29(24)35)28(34)20-8-11-26-19(14-20)12-13-37-26/h2-11,14-16,28H,12-13,17H2,1H3,(H,33,35)/t28-/m1/s1

InChIKey

MVMQGWXVSBNFLB-MUUNZHRXSA-N

Smiles

COc1ccc(cc1)c2cnc(nc2)N3Cc4c(=O)c5ccccc5[nH]c4[C@H]3c6ccc7c(c6)CCO7