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Substance Name: Maraviroc [INN:BAN:JAN]
RN: 376348-65-1
UNII: MD6P741W8A
InChIKey: GSNHKUDZZFZSJB-QYOOZWMWSA-N
Note
- AIDSinfo: Maraviroc, also known as Selzentry, is a chemokine receptor antagonist that acts as an entry inhibitor. It is designed to prevent HIV infection of CD4 cells by blocking chemokine receptor 5 (CCR5), a coreceptor necessary for HIV entry, from binding to HIV.
DailyMed: SELZENTRY is a CCR5 co-receptor antagonist indicated for combination antiretroviral treatment of adults infected with only CCR5-tropic HIV-1, who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents. Tropism testing is required for the appropriate use of SELZENTRY.
Molecular Formula
- C29-H41-F2-N5-O
Molecular Weight
- 513.6729
Classification Codes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- CCR5 Receptor Antagonists
- HIV Fusion Inhibitors
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Names and Synonyms
Name of Substance
- Maraviroc
- Maraviroc [INN:BAN:JAN]
MeSH Heading
- Maraviroc
Synonyms
- Celsentri
- HSDB 8021
- Isopropyl, 4,4-difluoro-N-((1S)-3-{(1R,3s,5S)-3-(3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)octan-8-yl}-1-phenylpropyl)cyclohexanecarboxamide
- Maraviroc
- MVC
- Selzentry
- UK 427857
- UK-427,857
- UNII-MD6P741W8A
Systematic Name
- Cyclohexanecarboxamide, 4,4-difluoro-N-((1S)-3-((3-exo)-3-(3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)-
Registry Numbers
CAS Registry Number
- 376348-65-1
FDA UNII
- MD6P741W8A
Other Registry Number
- 674782-29-7
System Generated Number
- 0376348651