Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Aprindine [USAN:INN:BAN]
RN: 37640-71-4
UNII: 5Y48085P9Q
InChIKey: NZLBHDRPUJLHCE-UHFFFAOYSA-N

Note

  • A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.

Molecular Formulas

  • C22-H30-N2
  • C40-H30-N2

Molecular Weight

  • 322.493
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Cardiac Depressant (Anti-Arrhythmic)
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Membrane Transport Modulators
  • Sodium Channel Blockers
  • Voltage-Gated Sodium Channel Blockers
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Aprindine
  • Aprindine [USAN:INN:BAN]

MeSH Heading

  • Aprindine

Synonyms

  • AC 1802
  • Aprindin
  • Aprindina
  • Aprindina [INN-Spanish]
  • Aprindine
  • Aprindinum
  • Aprindinum [INN-Latin]
  • Aprinidine
  • Compound 99170
  • N,N-Diethyl-N'-2-indanyl-N'-phenyl-1,3-propanediamine
  • N-(2,3-Dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-1,3-propanediamine
  • N-(3-(Diethylamino)propyl)-N-phenyl-2-indanamine
  • UNII-5Y48085P9Q

Systematic Name

  • 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-

Registry Numbers

CAS Registry Number

  • 37640-71-4

FDA UNII

  • 5Y48085P9Q

System Generated Number

  • 0037640714

Structure Descriptors

InChI

InChI=1S/C22H30N2/c1-3-23(4-2)15-10-16-24(21-13-6-5-7-14-21)22-17-19-11-8-9-12-20(19)18-22/h5-9,11-14,22H,3-4,10,15-18H2,1-2H3

InChIKey

NZLBHDRPUJLHCE-UHFFFAOYSA-N

Smiles

CCN(CC)CCCN(C1Cc2ccccc2C1)c3ccccc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 274mg/kg (274mg/kg)   Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 120-121 deg C   EXP
log P (octanol-water) 4.86 (none)   EXP
Water Solubility 6.520 mg/L 25 EST
Vapor Pressure 2.49E-07 mm Hg 25 EST
Henry's Law Constant 6.88E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.78E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.