Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Antipain
RN: 37691-11-5
UNII: 47V479BE6L
InChIKey: SDNYTAYICBFYFH-TUFLPTIASA-N

Note

  • An oligopeptide produced by various bacteria which acts as a protease inhibitor.

Molecular Formula

  • C27-H44-N10-O6

Molecular Weight

  • 604.709
 

Classification Codes

  • Enzyme Inhibitors
  • Mutation Data
  • Protease Inhibitors
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Antipain

MeSH Heading

  • Antipain

Synonyms

  • Antipain
  • CCRIS 3605
  • EINECS 253-631-0
  • UNII-47V479BE6L

Systematic Names

  • Antipain
  • L-Valinamide, N(sup 2)-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
  • L-Valinamide, N2-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
  • N2-(((1-Carboxyphenethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-L-valinamide

Registry Numbers

CAS Registry Number

  • 37691-11-5

FDA UNII

  • 47V479BE6L

System Generated Number

  • 0037691115

Structure Descriptors

InChI

1S/C27H44N10O6/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43)/t18-,19-,20-,21-/m0/s1

InChIKey

SDNYTAYICBFYFH-TUFLPTIASA-N

Smiles

C([C@@H](NC([C@@H](NC(N[C@H](C(=O)O)Cc1ccccc1)=O)CCCNC(=N)N)=O)C(C)C)(N[C@H](C=O)CCCNC(=N)N)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 187mg/kg (187mg/kg)   Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. Vol. 6, Pg. 57, 1976.
mouse LD50 oral > 500mg/kg (500mg/kg)   Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. Vol. 6, Pg. 57, 1976.
mouse LD50 subcutaneous > 500mg/kg (500mg/kg)   Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. Vol. 6, Pg. 57, 1976.