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Substance Name: Talizumab [USAN:INN:BAN]
RN: 380610-22-0
UNII: 9591BL735Z

Note

  • A humanized IgG1 monoclonal antibody against IgE that recognizes and masks an epitope in the CH3 region of IgE responsible for binding to the high-affinity Fc receptor on mast cells and basophils; increased the threshold of sensitivity to peanut antigen to a level that should afford protection from unintended ingestions.

Molecular Formulas

  • C6518-H10020-N1728-O2036-S42
  • Unspecified
 

Classification Codes

  • Treatment of Peanut Allergies
  • Treatment to Increase the Threshold for Peanut-Induced Anaphylaxisfrom Unintended Ingestion by Those with Peanut Allergy
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Links to Resources

Names and Synonyms

Name of Substance

  • Talizumab
  • Talizumab [USAN:INN:BAN]

Synonyms

  • Hu 901
  • Hu-901
  • Immunoglobulin G, anti-(human immunoglobulin E Fc region) (human-mouse monoclonal Hu901 gamma-chain), disulfide with human-mouse monoclonal Hu901 kappa-chain, dimer. Molecular weight is approximately 146,348 daltons
  • Talizumab
  • TNX 901
  • TNX-901
  • UNII-9591BL735Z

Systematic Name

  • Immunoglobulin G, anti-(human immunoglobulin E Fc region) (human-mouse monoclonal Hu901 gamma-chain), disulfide with human-mouse monoclonal Hu901 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 380610-22-0

FDA UNII

  • 9591BL735Z

System Generated Number

  • 0380610220