Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Streptomycin sulfate [USP:JAN]
RN: 3810-74-0
UNII: CW25IKJ202
InChIKey: QTENRWWVYAAPBI-YCRXJPFRSA-N

Note

  • An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.

Molecular Formulas

  • C21-H39-N7-O12.3/2H2-O4-S
  • C42-H78-N14-O24.H6-O12-S3

Molecular Weight

  • 1457.39
 

Classification Codes

  • Agricultural Chemical
  • Antibacterial (Tuberculostatic)
  • Drug / Therapeutic Agent
  • Germicide, Bactericide, Disinfectant
  • Human Data
  • Mutation Data
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Streptomycin sulfate [USP:JAN]

Synonyms

  • Agri-Strep
  • Agrimycin 17
  • Agristrep
  • AI3-50158
  • Ambistryn S
  • AS-15
  • Bis-(4-O-(2-O-(2-desoxy-2-methylamino-alpha-L-glucopyranosyl)-alpha-L-streptosyl)-L-streptidin)-trisulfat
  • Caswell No. 804A
  • CCRIS 5934
  • EINECS 223-286-0
  • EPA Pesticide Chemical Code 006310
  • Estreptomicina
  • Estreptopanto
  • NSC 14083
  • Phytomycin
  • Plantomycin
  • Streoikub
  • Streotitgebat
  • Strep-gran
  • Strepcin
  • Strepsulfat
  • Streptomycin A sulfate
  • Streptomycin sesquisulfate
  • Streptomycin sulfate
  • Streptomycin sulfate (2:3) (salt)
  • Streptomycin sulphate
  • Streptomycin sulphate B.P
  • Streptomycinium sulfuricum
  • Streptomyzinsulfat
  • Streptorex
  • Strepvet
  • Strycin
  • UNII-CW25IKJ202
  • Vetstrep

Systematic Names

  • D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
  • D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1->4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)
  • D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1.fwdarw.4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
  • Streptomycin sulfate (2:3)
  • Streptomycin sulphate
  • Streptomycin, sulfate (2:3) (salt)

Superlist Name

  • Streptomycin sulfate

Mixture Name

  • Intromycin

Registry Numbers

CAS Registry Number

  • 3810-74-0

FDA UNII

  • CW25IKJ202

Other Registry Numbers

  • 15105-93-8
  • 298-39-5
  • 67479-32-7
  • 8018-05-1
  • 82115-93-3
  • 85027-84-5

Related Registry Number

  • 57-92-1 (Parent)

System Generated Number

  • 0003810740

Molecular Formulas

Molecular Formulas

  • C21-H39-N7-O12.3/2H2-O4-S
  • C42-H78-N14-O24.H6-O12-S3

Molecular Formula Fragments

  • C21-H39-N7-O12
  • C42-H78-N14-O24
  • COMPONENT
  • H2-O4-S
  • H6-O12-S3

Structure Descriptors

InChI

1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1

InChIKey

QTENRWWVYAAPBI-YCRXJPFRSA-N

Smiles

S(O)(=O)(=O)O.O1[C@H]([C@H]([C@@H]([C@H]([C@@H]1CO)O)O)NC)O[C@@H]1[C@]([C@@H](O[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]([C@H]([C@@H]1NC(N)=N)O)NC(=N)N)C)(C=O)O.O1[C@H]([C@H]([C@@H]([C@H]([C@@H]1CO)O)O)NC)O[C@@H]1[C@]([C@@H](O[C@H]1O[C@H]1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(N)=N)O)NC(=N)N)O)O)C)(C=O)O.S(=O)(=O)(O)O.S(=O)(=O)(O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
hamster LD50 oral 400mg/kg (400mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 14, Pg. 510, 1969.
infant TDLo intraperitoneal 170mg/kg (170mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
British Medical Journal. Vol. 1, Pg. 557, 1961.
mouse LD50 intravenous 90200ug/kg (90.2mg/kg)   Antibiotiki. Vol. 18, Pg. 444, 1973.
mouse LD50 oral 430mg/kg (430mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
mouse LD50 subcutaneous 403mg/kg (403mg/kg)   Antibiotics Annual. Vol. 4, Pg. 574, 1956/1957.
rat LD50 oral 430mg/kg (430mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
rat LD50 subcutaneous 600mg/kg (600mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 597, 1962.