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Substance Name: Desoximetasone [USAN:USP:INN:BAN]
RN: 382-67-2
UNII: 4E07GXB7AU
InChIKey: VWVSBHGCDBMOOT-IIEHVVJPSA-N

Note

  • A topical anti-inflammatory glucocorticoid used in DERMATOSES, skin allergies, PSORIASIS, etc.

Molecular Formula

  • C22-H29-F-O4

Molecular Weight

  • 376.4651
 

Classification Codes

  • Adrenal Cortex Hormones
  • Anti-Inflammatory
  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Hormone
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Desoximetasone
  • Desoximetasone [USAN:USP:INN:BAN]

MeSH Heading

  • Desoximetasone

Synonyms

  • 17-Deoxymethansone
  • 17-Desoximethasone
  • 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
  • 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • A 41-304
  • A 41304
  • A-41-304
  • BRN 2228097
  • Deoxymethasone
  • Desossimetasone
  • Desossimetasone [DCIT]
  • Desoximetasona
  • Desoximetasona [INN-Spanish]
  • Desoximetasone
  • Desoximetasonum
  • Desoximetasonum [INN-Latin]
  • Desoxymethasone
  • EINECS 206-845-3
  • Esperson
  • Flubason
  • HOE 304
  • Ibaril
  • R 2113
  • Stiedex
  • Topicort
  • Topicort LP
  • Topisolon
  • UNII-4E07GXB7AU

Systematic Names

  • Desoximetasone
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11beta,16alpha)-

Registry Numbers

CAS Registry Number

  • 382-67-2

FDA UNII

  • 4E07GXB7AU

System Generated Number

  • 0000382672

Structure Descriptors

InChI

1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1

InChIKey

VWVSBHGCDBMOOT-IIEHVVJPSA-N

Smiles

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 217 deg C   EXP
log P (octanol-water) 2.35 (none)   EXP
Water Solubility 42.1 mg/L 25 EST
Vapor Pressure 3.15E-12 mm Hg 25 EST
Henry's Law Constant 4.59E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 7.08E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.