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Substance Name: l-Methylephedrine hydrochloride [JAN]
RN: 38455-90-2
UNII: 8ONA78V6FO
InChIKey: NTCYWJCEOILKNG-ROLPUNSJSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C11-H17-N-O.Cl-H

Molecular Weight

  • 215.7222
 
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Names and Synonyms

Name of Substance

  • l-Methylephedrine hydrochloride [JAN]

Synonyms

  • (-)-Methylephedrine hydrochloride
  • (R-(R*,S*))-alpha-(1-(Dimethylamino)ethyl)benzenemethanol hydrochloride
  • EINECS 253-947-9
  • l-Erythro-methylephedrine hydrochloride
  • l-Methylephedrine hydrochloride
  • Methy F
  • N-Methylephedrine hydrochloride
  • NSC 42289
  • UNII-8ONA78V6FO

Systematic Names

  • Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-, hydrochloride, (R-(R*,S*))-
  • N-Methylephedrine hydrochloride

Registry Numbers

CAS Registry Number

  • 38455-90-2

FDA UNII

  • 8ONA78V6FO

System Generated Number

  • 0038455902

Molecular Formulas

Molecular Formula

  • C11-H17-N-O.Cl-H

Molecular Formula Fragments

  • C11-H17-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C11H17NO.ClH/c1-9(12(2)3)11(13)10-7-5-4-6-8-10;/h4-9,11,13H,1-3H3;1H/t9-,11-;/m0./s1

InChIKey

NTCYWJCEOILKNG-ROLPUNSJSA-N

Smiles

Cl.C[C@@H]([C@H](O)c1ccccc1)N(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 144mg/kg (144mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 688, 1958.
mouse LD50 intraperitoneal 216mg/kg (216mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
mouse LD50 subcutaneous 699mg/kg (699mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 53, Pg. 638, 1957.