Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Lapatinib Ditosylate [USAN]
RN: 388082-78-8
UNII: G873GX646R
InChIKey: XNRVGTHNYCNCFF-UHFFFAOYSA-N

Note

  • An EGFR-ErbB-2 inhibitor.

Molecular Formula

  • C29-H26-Cl-F-N4-O4-S.2C7-H8-O3-S.H2-O

Molecular Weight

  • 943.4866
 

Classification Codes

  • Anti-Neoplastic Agent
  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Protein Kinase Inhibitors
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Lapatinib Ditosylate [USAN]

Synonyms

  • Lapatinib ditosylate monohydrate
  • N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate) monohydrate
  • Tykerb
  • Tyverb
  • UNII-G873GX646R

Systematic Name

  • 4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl), bis(4-methylbenzenesulfonate), monohydrate

Registry Numbers

CAS Registry Number

  • 388082-78-8

FDA UNII

  • G873GX646R

System Generated Number

  • 0388082788

Molecular Formulas

Molecular Formula

  • C29-H26-Cl-F-N4-O4-S.2C7-H8-O3-S.H2-O

Molecular Formula Fragments

  • C29-H26-Cl-F-N4-O4-S
  • C7-H8-O3-S
  • H2-O

Structure Descriptors

InChI

1S/C29H26ClFN4O4S.2C7H8O3S.H2O/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19;2*1-6-2-4-7(5-3-6)11(8,9)10;/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35);2*2-5H,1H3,(H,8,9,10);1H2

InChIKey

XNRVGTHNYCNCFF-UHFFFAOYSA-N

Smiles

Cc1ccc(cc1)S(=O)(=O)O.Cc1ccc(cc1)S(=O)(=O)O.CS(=O)(=O)CCNCc1ccc(o1)c2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5cccc(c5)F.O