Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: ICR 340
RN: 38915-28-5
InChIKey: PUURHJFGPZZDJF-UHFFFAOYSA-N

Note

  • ICR acridine half-mustard cpd.

Classification Codes

  • Mutation Data
  • Tumor Data

Molecular Formula

  • C20-H24-Cl2-N4-O.2Cl-H

Molecular Weight

  • 480.264
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • ICR 340

Synonyms

  • CCRIS 7020
  • ICR 340
  • NSC 133482

Systematic Names

  • 1,3-Propanediamine, N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)-N-ethyl-, dihydrochloride (9CI)
  • Benzo(b)(1,5)naphthyridine, 7-chloro-10-(3-(N-(2-chloroethyl)-N-ethyl)aminopropylamino)-2-methoxy-, dihydrochloride
  • ICR 340
  • N-(2-Chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)-N-ethyl-1,3-propanediamine, dihydrochloride

Registry Numbers

CAS Registry Number

  • 38915-28-5

Other Registry Numbers

  • 12798-08-2
  • 54174-16-2

System Generated Number

  • 0038915285

Molecular Formulas

Molecular Formula

  • C20-H24-Cl2-N4-O.2Cl-H

Molecular Formula Fragments

  • C20-H24-Cl2-N4-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C20H24Cl2N4O.2ClH/c1-3-26(12-9-21)11-4-10-23-19-15-6-5-14(22)13-17(15)24-16-7-8-18(27-2)25-20(16)19;;/h5-8,13H,3-4,9-12H2,1-2H3,(H,23,24);2*1H

InChIKey

PUURHJFGPZZDJF-UHFFFAOYSA-N

Smiles

c12c(c3c(cc(Cl)cc3)nc1ccc([n+]2)OC)NCCC[N@@H+](CCCl)CC.[ClH-].[ClH-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD20 intraperitoneal 3737ug/kg (3.737mg/kg)   Journal of Medicinal Chemistry. Vol. 15, Pg. 739, 1972.
mouse LDLo intravenous 7mg/kg (7mg/kg)   Cancer Research. Vol. 36, Pg. 2423, 1976.