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Substance Name: Alminoprofen [INN:JAN]
RN: 39718-89-3
UNII: 0255AHR9GJ
InChIKey: FPHLBGOJWPEVME-UHFFFAOYSA-N
Molecular Formula
- C13-H17-N-O2
Molecular Weight
- 219.282
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Drug / Therapeutic Agent
- Peripheral Nervous System Agents
- Reproductive Effect
- Sensory System Agents
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Names and Synonyms
Name of Substance
- Alminoprofen
- Alminoprofen [INN:JAN]
Synonyms
- 2-(4-((2-Methylallyl)amino)phenyl)propansaeure
- 2-(4-(Methallylamino)phenyl)propionic acid
- 4-((2-Methylallyl)amino)hydratropasaeure
- Acide (methallylamino-4 phenyl)-2 propionique
- Acide (methallylamino-4 phenyl)-2 propionique [French]
- Alminoprofen
- Alminoprofene
- Alminoprofene [INN-French]
- Alminoprofeno
- Alminoprofeno [INN-Spanish]
- Alminoprofeno [Spanish]
- Alminoprofenum
- Alminoprofenum [INN-Latin]
- alpha-Methyl-4-((2-methyl-2-propenyl)amino)benzeneacetic acid
- Benzeneacetic acid, alpha-methyl-4-((2-methyl-2-propenyl)amino)-
- BRN 2373633
- EB 382
- EB-382
- EINECS 254-604-6
- Minalfene
- p-((2-Methylallyl)amino)hydratropic acid
- UNII-0255AHR9GJ
Systematic Names
- Alminoprofen
- Benzeneacetic acid, alpha-methyl-4-((2-methyl-2-propenyl)amino)-
- p-((2-Methylallyl)amino)hydratropic acid
- Propionic acid, 2-(4-(methallylamino)phenyl)-
Registry Numbers
CAS Registry Number
- 39718-89-3
FDA UNII
- 0255AHR9GJ
System Generated Number
- 0039718893
Structure Descriptors
InChI
1S/C13H17NO2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13(15)16/h4-7,10,14H,1,8H2,2-3H3,(H,15,16)InChIKey
FPHLBGOJWPEVME-UHFFFAOYSA-NSmiles
c1c([C@@H](C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mammal (species unspecified) | LD50 | oral | 1780mg/kg (1780mg/kg) | Drugs of the Future. Vol. 9, Pg. 165, 1984. | |
mouse | LD50 | intraperitoneal | 705mg/kg (705mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 2093, 1986. |
mouse | LD50 | oral | 1520mg/kg (1520mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 2093, 1986. |
mouse | LD50 | subcutaneous | 980mg/kg (980mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 2093, 1986. |
rat | LD50 | intraperitoneal | 700mg/kg (700mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 2093, 1986. |
rat | LD50 | oral | 550mg/kg (550mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 2093, 1986. |
rat | LD50 | subcutaneous | 660mg/kg (660mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14, Pg. 2093, 1986. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 107 | deg C | EXP | |
log P (octanol-water) | 2.870 | (none) | EST | |
Atmospheric OH Rate Constant | 1.14E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.