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Substance Name: Indanazoline hydrochloride
RN: 40507-80-0
UNII: Z364A90IV8
InChIKey: GZVYIVIJAOMGJT-UHFFFAOYSA-N

Classification Codes

  • alpha-Sympathomimetic
  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C12-H15-N3.Cl-H

Molecular Weight

  • 237.732
 
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Names and Synonyms

Results Name

  • Indanazoline hydrochloride

Name of Substance

  • Indanazoline hydrochloride

Synonyms

  • E-VA-16
  • EINECS 254-945-0
  • Farial
  • Indanazoline HCl
  • Indanazoline hydrochloride
  • N-(2-Imidazoline-2-yl)-N-(4-indanyl)amin-monohydrochlorid
  • N-(2-Imidazoline-2-yl)-N-(4-indanyl)amin-monohydrochlorid [German]
  • N-(2-Imidazoline-2-yl)-N-(4-indanyl)amine monohydrochloride
  • UNII-Z364A90IV8

Systematic Names

  • 1H-Imidazol-2-amine, N-(2,3-dihydro-1H-inden-4-yl)-4,5-dihydro-, monohydrochloride (9CI)
  • 2-Imidazoline, 2-(4-indanylamino)-, hydrochloride
  • N-(2,3-Dihydro-1H-inden-4-yl)-4,5-dihydro-1H-imidazol-2-amine monohydrochloride

Registry Numbers

CAS Registry Number

  • 40507-80-0

FDA UNII

  • Z364A90IV8

Other Registry Number

  • 56601-85-5

Related Registry Number

  • 40507-78-6 (Parent)

System Generated Number

  • 0040507800

Molecular Formulas

Molecular Formula

  • C12-H15-N3.Cl-H

Molecular Formula Fragments

  • C12-H15-N3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C12H15N3.ClH/c1-3-9-4-2-6-11(10(9)5-1)15-12-13-7-8-14-12;/h2,4,6H,1,3,5,7-8H2,(H2,13,14,15);1H

InChIKey

GZVYIVIJAOMGJT-UHFFFAOYSA-N

Smiles

C1(=NCCN1)Nc1c2CCCc2ccc1.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 316mg/kg (316mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1760, 1980.
mouse LD50 intravenous 22300ug/kg (22.3mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1760, 1980.
mouse LD50 oral 179mg/kg (179mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1760, 1980.
rat LD50 intravenous 16300ug/kg (16.3mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1760, 1980.
rat LD50 oral 481mg/kg (481mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1760, 1980.