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Substance Name: Rifamycin SV, 8-(diethylaminomethyl)-
RN: 4075-41-6
InChIKey: PHNHLMKMZYDVBQ-XCAXMWIJSA-N
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C42-H58-N2-O12
Molecular Weight
- 782.9222
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Names and Synonyms
Results Name
- Rifamycin SV, 8-(diethylaminomethyl)-
Synonyms
- NCI 145-666
- NSC 173706
- PF-42
- Rifamycin PF 42
- Rifamycin SV, 8-(diethylaminomethyl)-
Systematic Name
- 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(diethylaminomethyl)-, 21-acetate
Registry Numbers
CAS Registry Number
- 4075-41-6
System Generated Number
- 0004075416
Structure Descriptors
InChI
1S/C42H58N2O12/c1-12-44(13-2)19-27-32-37(50)30-29(36(27)49)31-39(25(8)35(30)48)56-42(10,40(31)51)54-18-17-28(53-11)22(5)38(55-26(9)45)24(7)34(47)23(6)33(46)20(3)15-14-16-21(4)41(52)43-32/h14-18,20,22-24,28,33-34,38,46-50H,12-13,19H2,1-11H3,(H,43,52)/b15-14+,18-17+,21-16-/t20-,22+,23-,24+,28+,33-,34+,38+,42+/m1/s1InChIKey
PHNHLMKMZYDVBQ-XCAXMWIJSA-NSmiles
CCN(CC)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 400mg/kg (400mg/kg) | Chemotherapia. Vol. 12, Pg. 155, 1967. | |
mouse | LD50 | intravenous | 205mg/kg (205mg/kg) | "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977Vol. -, Pg. 531, 1977. | |
mouse | LD50 | oral | > 2gm/kg (2000mg/kg) | Chemotherapia. Vol. 12, Pg. 155, 1967. |