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Substance Name: Midodrine [INN:BAN]
RN: 42794-76-3
UNII: 6YE7PBM15H
InChIKey: PTKSEFOSCHHMPD-UHFFFAOYSA-N

Note

  • An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.

Molecular Formula

  • C12-H18-N2-O4

Molecular Weight

  • 254.2842
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic Agonists
  • Adrenergic alpha-1 Receptor Agonists
  • Adrenergic alpha-Agonists
  • Autonomic Agents
  • Cardiovascular Agents
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Sympathomimetics
  • Vasoconstrictor Agents

Names and Synonyms

Name of Substance

  • Midodrine
  • Midodrine [INN:BAN]

MeSH Heading

  • Midodrine

Synonyms

  • (RS)-N'-(beta-Hydroxy-2,5-dimethoxy-phenethyl)glycinamid
  • 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol
  • 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid
  • 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethylacetamide
  • DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid
  • EINECS 255-945-3
  • HSDB 7854
  • Midodrin
  • Midodrina
  • Midodrina [INN-Spanish]
  • Midodrine
  • Midodrinum
  • Midodrinum [INN-Latin]
  • St 1085
  • UNII-6YE7PBM15H

Systematic Names

  • Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-
  • Midodrine

Registry Numbers

CAS Registry Number

  • 42794-76-3

FDA UNII

  • 6YE7PBM15H

Other Registry Number

  • 97476-58-9

Related Registry Number

  • 3092-17-9 (mono-hydrochloride)

System Generated Number

  • 0042794763

Structure Descriptors

InChI

1S/C12H18N2O4/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16)

InChIKey

PTKSEFOSCHHMPD-UHFFFAOYSA-N

Smiles

COc1ccc(c(c1)C(CNC(=O)CN)O)OC

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) -0.940 (none)   EST
Atmospheric OH Rate Constant 9.20E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.