Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Vinpocetine [USAN:INN:BAN:JAN]
RN: 42971-09-5
UNII: 543512OBTC
InChIKey: DDNCQMVWWZOMLN-IRLDBZIGSA-N

Molecular Formula

  • C22-H26-N2-O2

Molecular Weight

  • 350.4594
 

Classification Codes

  • Cardiovascular Agents
  • Central Nervous System Agents
  • Drug / Therapeutic Agent
  • Enzyme Inhibitors
  • Neuroprotective Agents
  • Nootropic Agents
  • Phosphodiesterase Inhibitors
  • Protective Agents
  • Reproductive Effect
  • Vasodilator Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Vinpocetine
  • Vinpocetine [USAN:INN:BAN:JAN]

Synonyms

  • (+)-Apovincaminic acid ethyl ester
  • (+)-cis-Apovincaminic acid ethyl ester
  • 3-alpha,16-alpha-Apovincaminic acid ethyl ester
  • Apovincaminate d'ethyle
  • Apovincaminate d'ethyle [French]
  • Apovincaminic acid ethyl ester
  • AY 27,255
  • AY-27,255
  • BRN 0900803
  • Cavinton
  • cis-Apovincaminic acid ethyl ester
  • EINECS 256-028-0
  • Ethyl (+)-apovincaminate
  • Ethyl (+)-cis-apovincaminate
  • Ethyl apovincamin-22-oate
  • RGH 4405
  • RGH-4405
  • TCV-3B
  • UNII-543512OBTC
  • Vinpocetine
  • Vinpocetinum
  • Vinpocetinum [INN-Latin]

Systematic Names

  • Eburnamenine-14-carboxylic acid, ethyl ester, (3-alpha,16-alpha)-
  • Eburnamenine-14-carboxylic acid, ethyl ester, (3alpha,16alpha)-
  • Vinpocetine

Registry Numbers

CAS Registry Number

  • 42971-09-5

FDA UNII

  • 543512OBTC

Other Registry Numbers

  • 115986-87-3
  • 80038-06-8

System Generated Number

  • 0042971095

Structure Descriptors

InChI

1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1

InChIKey

DDNCQMVWWZOMLN-IRLDBZIGSA-N

Smiles

CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@H]23)n1c5ccccc45

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 117mg/kg (117mg/kg)   Yakkyoku. Pharmacy. Vol. 35, Pg. 1919, 1984.
mouse LD50 intravenous 45mg/kg (45mg/kg)   Yakkyoku. Pharmacy. Vol. 35, Pg. 1919, 1984.
mouse LD50 oral 534mg/kg (534mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1938, 1976.
rat LD50 intraperitoneal 119mg/kg (119mg/kg)   Yakkyoku. Pharmacy. Vol. 35, Pg. 1919, 1984.
rat LD50 intravenous 32mg/kg (32mg/kg)   Yakkyoku. Pharmacy. Vol. 35, Pg. 1919, 1984.
rat LD50 oral 503mg/kg (503mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1938, 1976.