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Substance Name: Oxymetholone [USAN:USP:INN:BAN:JAN]
RN: 434-07-1
UNII: L76T0ZCA8K
InChIKey: ICMWWNHDUZJFDW-DHODBPELSA-N
Note
- A synthetic hormone with anabolic and androgenic properties. It is used mainly in the treatment of anemias. According to the Fourth Annual Report on Carcinogens (NTP 85-002), this compound may reasonably be anticipated to be a carcinogen. (From Merck Index, 11th ed).
Molecular Formula
- C21-H32-O3
Molecular Weight
- 332.4808
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Anabolic Agents
- Androgen
- Androgens
- Drug / Therapeutic Agent
- Hormone
- Hormones
- Hormones, Hormone Substitutes, and Hormone Antagonists
- Human Data
- Mutation Data
- Reproductive Effect
- Tumor Data
Superlist Classification Codes
- DEA Schedule III
- Reasonably Anticipated to be a Carcinogen
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NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
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Names and Synonyms
Name of Substance
- Oxymetholone
- Oxymetholone [USAN:USP:INN:BAN:JAN]
MeSH Heading
- Oxymetholone
Synonyms
- 17-alpha-Methyl-2-hydroxymethylene-17-hydroxy-5-alpha-androstan-3-one
- 17-beta-Hydroxy-2-(hydroxymethylene)-17-alpha-methyl-5-alpha-androstan-3-one
- 17-beta-Hydroxy-2-hydroxymethylene-17-alpha-methyl-3-androstanone
- 17-Hydroxy-2-(hydroxymethylene)-17-methyl-5-alpha-17-beta-androst-3-one
- 17-Hydroxy-5-alpha-androstan-3-one
- 17alpha-Methyl-2-hydroxymethylene-17-hydroxy-5alpha-androstan-3-one
- 17beta-Hydroxy-2-(hydroxymethylene)-17-methyl-5alpha-androstan-3-one
- 2-Hydroxymethylene-17-alpha-methyl-17-beta-hydroxy-3-androstanone
- 2-Hydroxymethylene-17-alpha-methyl-5-alpha-androstan-17-beta-ol-3-one
- 2-Hydroxymethylene-17-alpha-methyl-dihydrotestosterone
- 2-Hydroxymethylene-17alpha-methyl-17beta-hydroxy-3-adrostanone
- 2-Hydroxymethylene-17alpha-methyl-17beta-hydroxy-5alpha-androstan-3-one
- 2-Hydroxymethylene-17alpha-methyl-5alpha-androstan-17beta-ol-3-one
- 2-Hydroxymethylene-17alpha-methylandrostan-17beta-ol-3-one
- 2-Hydroxymethylene-17alpha-methyldihydrotestosterone
- 4,5-Dihydro-2-hydroxymethylene-17-alpha-methyltestosterone
- 4,5alpha-Dihydro-2-hydroxymethylene-17alpha-methyltestosterone
- 5alpha-Androstan-3-one, 17beta-hydroxy-2-(hydroxymethylene)-17-methyl-
- Adroidin
- Adroyd
- Anadrol
- Anadrol-50
- Anadroyd
- Anapolon
- Anasteron
- Anasterone
- Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (alpha,17beta)-
- Becorel
- CCRIS 492
- CI 406
- CI-406
- Dynasten
- EINECS 207-098-6
- HMD
- HSDB 3374
- Methabol
- Nastenon
- NSC 26198
- NSC-26,198
- Ossimetolone
- Ossimetolone [DCIT]
- Oximetalonu
- Oximetholonum
- Oximetolona
- Oximetolona [INN-Spanish]
- Oxitosona-50
- Oxymethalone
- Oxymethenolone
- Oxymetholone
- Oxymetholonum
- Oxymetholonum [INN-Latin]
- Pavisoid
- Plenastril
- Protanabol
- Roboral
- Synasteron
- UNII-L76T0ZCA8K
- Zenalosyn
Systematic Names
- 5-alpha,17-beta-Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-
- 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-(hydroxymethylene)-17-methyl- (8CI)
- Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5-alpha,17-beta)- (9CI)
- Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5alpha,17beta)-
- Androstano(2,3-c)(1,2,5)oxadiazol-17-ol, 17-methyl-, (5-alpha,17-beta)- (9CI)
- Oxymetholone
Superlist Names
- 17alpha-Methyl-2-hydroxymethylene-17beta-hydroxy-5alpha-androstan-3-one
- Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5alpha,17beta)-
- DEA No. 4000
- Oxymetholone
- Oxymetholone [Androgenic steroids, anabolic]
Registry Numbers
CAS Registry Number
- 434-07-1
FDA UNII
- L76T0ZCA8K
System Generated Number
- 0000434071
Structure Descriptors
InChI
InChI=1S/C21H32O3/c1-19-11-13(12-22)18(23)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,22,24H,4-11H2,1-3H3/b13-12-/t14-,15+,16-,17-,19-,20-,21-/m0/s1InChIKey
ICMWWNHDUZJFDW-DHODBPELSA-NSmiles
C[C@]1(O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
human | TDLo | oral | 46mg/kg/14W-I (46mg/kg) | LIVER: LIVER FUNCTION TESTS IMPAIRED | JAMA, Journal of the American Medical Association. Vol. 240, Pg. 243, 1978. |
rat | LD50 | intraperitoneal | > 1gm/kg (1000mg/kg) | Drugs in Japan Vol. 6, Pg. 156, 1982. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 179 | deg C | EXP | |
log P (octanol-water) | 3.610 | (none) | EST | |
Atmospheric OH Rate Constant | 1.12E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.