Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Timonacic [INN]
RN: 444-27-9
UNII: E5913T3IBL
InChIKey: DZLNHFMRPBPULJ-UHFFFAOYSA-N

Note

  • Active against thimerosal intoxication; acts on cell membranes of tumor cells causing reverse transformation to normal cells.

Molecular Formula

  • C4-H7-N-O2-S

Molecular Weight

  • 133.1703
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Antidotes
  • Antineoplastic Agents
  • Antioxidants
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Protective Agents
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Thiazolidine-4-carboxylic acid
  • Timonacic [INN]

Synonyms

  • 4-Carboxythiazolidine
  • 4-Thiazolidinecarboxylic acid
  • Acide DL thiazolidine carboxylique-4
  • Acide DL thiazolidine carboxylique-4 [French]
  • Acide thiazolidine-4-carboxylique
  • Acide thiazolidine-4-carboxylique [French]
  • CCRIS 8099
  • Detoxepa
  • DL-Thiaproline
  • DL-Thiazolidinecarboxylic acid
  • EINECS 207-146-6
  • EINECS 242-945-3
  • Hepalidine
  • Heparegene
  • Norgamem
  • NSC 25855
  • T-4CA
  • Thiaproline
  • Thiazolidine-4-carboxylic acid
  • Thiazolidinecarboxylic acid (VAN)
  • Thioproline
  • Tiazolidin
  • Timonacic
  • Timonacico
  • Timonacico [INN-Spanish]
  • Timonacicum
  • Timonacicum [INN-Latin]
  • UNII-E5913T3IBL
  • USAF A-3701
  • USAF C-1

Systematic Names

  • 4-Thiazolidinecarboxylic acid
  • Timonacic

Registry Numbers

CAS Registry Number

  • 444-27-9

FDA UNII

  • E5913T3IBL

Other Registry Numbers

  • 19291-02-2
  • 2756-91-4
  • 60731-25-1

Related Registry Number

  • 35041-11-3 (hydrochloride salt)

System Generated Number

  • 0000444279

Structure Descriptors

InChI

1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)

InChIKey

DZLNHFMRPBPULJ-UHFFFAOYSA-N

Smiles

C1C(NCS1)C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 420mg/kg (420mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR

KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED
Lancet. Vol. 1, Pg. 778, 1981.
mouse LD50 intraperitoneal 100mg/kg (100mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 oral 400mg/kg (400mg/kg)   Gazzetta Medica Italiana. Vol. 131, Pg. 265, 1972.
mouse LD50 unreported 300mg/kg (300mg/kg)   Lancet. Vol. 1, Pg. 68, 1980.
rat LD50 intraperitoneal 494mg/kg (494mg/kg) LIVER: OTHER CHANGES Drugs under Experimental and Clinical Research. Vol. 13, Pg. 399, 1987.
rat LD50 oral 875mg/kg (875mg/kg) LIVER: OTHER CHANGES Drugs under Experimental and Clinical Research. Vol. 13, Pg. 399, 1987.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 196.5 deg C   EXP
log P (octanol-water) -3.040 (none)   EST
Atmospheric OH Rate Constant 1.25E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.