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Substance Name: Ezetimibe mixture with Simvastatin
RN: 444313-53-5
InChIKey: PNAMDJVUJCJOIX-IUNFJCKHSA-N

Notes

  • A pharmaceutical preparation of ezetimibe and simvastatin that is used in the treatment of HYPERCHOLESTEROLEMIA and HYPERLIPIDEMIAS.
  • Consists of ezetimibe and simvastatin; used to treat hypercholesterolemia.

Molecular Formula

  • C25-H38-O5.C24-H21-F2-N-O3

Molecular Weight

  • 828.0001
 

Classification Codes

  • Anticholesteremic Agents
  • Antihyperlipidemic
  • Antimetabolites
  • Hypolipidemic Agents
  • Lipid Regulating Agents

Names and Synonyms

Results Name

  • Ezetimibe mixture with Simvastatin

Name of Substance

  • Ezetimibe-simvastatin combination

MeSH Heading

  • Ezetimibe, Simvastatin Drug Combination

Synonyms

  • Ezetimibe and simvastatin
  • Ezetimibe mixture with Simvastatin
  • Ezetimibe/simvastatin
  • INEGY
  • MK 0653A
  • Simvastatin and ezetimibe
  • Vytorin

Systematic Name

  • Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, mixt. with (3R,4S)-1-(4-fluorophenyl)-3-((3S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-2-azetidinone

Registry Numbers

CAS Registry Number

  • 444313-53-5

System Generated Number

  • 0444313535

Molecular Formulas

Molecular Formula

  • C25-H38-O5.C24-H21-F2-N-O3

Molecular Formula Fragments

  • C24-H21-F2-N-O3
  • C25-H38-O5
  • COMPONENT

Structure Descriptors

InChI

1S/C25H38O5.C24H21F2NO3/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19;25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3;1-12,21-23,28-29H,13-14H2/t15-,16-,18+,19+,20-,21-,23-;21-,22+,23-/m01/s1

InChIKey

PNAMDJVUJCJOIX-IUNFJCKHSA-N

Smiles

CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C.c1cc(ccc1[C@@H]2[C@H](C(=O)N2c3ccc(cc3)F)CC[C@@H](c4ccc(cc4)F)O)O