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Substance Name: Diiodobenzotepa
RN: 4460-32-6
InChIKey: BFKKCDNAUZMDOX-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C11-H12-I2-N3-O2-P

Molecular Weight

  • 503.009
 
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Names and Synonyms

Name of Substance

  • Diiodobenzotepa

Synonyms

  • 2,5-Diodobenzo-TEPA
  • 5-20-01-00115 (Beilstein Handbook Reference)
  • BRN 1324621
  • Diiodbenzoteph
  • Diiodobenzotef
  • Diiodobenzotepa
  • Diiodobenzoteph
  • Dijodbenzotef
  • N-(Bis(1-aziridinyl)phosphinyl)-2,5-diiodobenzamide
  • N-2,5-Diiodobenzoyl-N',N',N'',N''-diethylenephosphortriamide
  • NSC 167781
  • Phosphinic amide, P,P-bis(1-aziridinyl)-2,5-diiodobenzoyl-

Systematic Name

  • Benzamide, N-(bis(1-aziridinyl)phosphinyl)-2,5-diiodo-

Registry Numbers

CAS Registry Number

  • 4460-32-6

System Generated Number

  • 0004460326

Structure Descriptors

InChI

1S/C11H12I2N3O2P/c12-8-1-2-10(13)9(7-8)11(17)14-19(18,15-3-4-15)16-5-6-16/h1-2,7H,3-6H2,(H,14,17,18)

InChIKey

BFKKCDNAUZMDOX-UHFFFAOYSA-N

Smiles

P(NC(c1c(ccc(c1)I)I)=O)(N1CC1)(N1CC1)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intraperitoneal 500mg/kg (500mg/kg)   Russian Pharmacology and Toxicology Vol. 41, Pg. 135, 1978.
rat LD50 oral 500mg/kg (500mg/kg)   Pharmaceutical Chemistry Journal Vol. 12, Pg. 689, 1978.
rat LD50 parenteral 300mg/kg (300mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Farmakologiya i Toksikologiya Vol. 7, Pg. 91, 1972.
rat LD50 unreported 850mg/kg (850mg/kg)   Pharmaceutical Chemistry Journal Vol. 16, Pg. 626, 1982.