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Substance Name: Ethoxzolamide [USP]
RN: 452-35-7
UNII: Z52H4811WX
InChIKey: OUZWUKMCLIBBOG-UHFFFAOYSA-N

Note

  • A carbonic anhydrase inhibitor used as diuretic and in glaucoma. It may cause hypokalemia.

Molecular Formula

  • C9-H10-N2-O3-S2

Molecular Weight

  • 258.321
 

Classification Codes

  • Carbonic Anhydrase Inhibitors
  • Diuretics
  • Drug / Therapeutic Agent
  • Enzyme Inhibitors
  • Natriuretic Agents
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Ethoxzolamide
  • Ethoxzolamide [USP]

MeSH Heading

  • Ethoxzolamide

Synonyms

  • 2-Benzothiazolesulfonamide, 6-ethoxy-
  • 4-27-00-04404 (Beilstein Handbook Reference)
  • 6-Ethoxy-2-benzothiazolesulfonamide
  • AI3-50805
  • BRN 0212240
  • Cardrase
  • Diuretic C
  • EINECS 207-199-5
  • Ethamide
  • Ethoxazolamide
  • Ethoxyzolamide
  • Ethoxzolamide
  • Etoxzolamide
  • Glaucotensil
  • HSDB 3268
  • Mingoral
  • NSC 10679
  • U-4191
  • UNII-Z52H4811WX

Systematic Names

  • 2-Benzothiazolesulfonamide, 6-ethoxy-
  • 6-Ethoxybenzothiazole-2-sulphonamide

Registry Numbers

CAS Registry Number

  • 452-35-7

FDA UNII

  • Z52H4811WX

System Generated Number

  • 0000452357

Structure Descriptors

InChI

InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)

InChIKey

OUZWUKMCLIBBOG-UHFFFAOYSA-N

Smiles

CCOc1ccc2nc(sc2c1)S(=O)(=O)N

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 189 deg C   EXP
log P (octanol-water) 2.01 (none)   EXP
Water Solubility 40 mg/L   EXP
Vapor Pressure 9.33E-08 mm Hg 25 EST
Henry's Law Constant 2.30E-12 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.08E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.