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Substance Name: Motesanib [USAN:INN]
RN: 453562-69-1
UNII: U1JK633AYI
InChIKey: RAHBGWKEPAQNFF-UHFFFAOYSA-N

Note

  • A c-KIT protein inhibitor and antineoplastic agent.

Molecular Formula

  • C22-H23-N5-O

Molecular Weight

  • 373.4577
 

Classification Codes

  • Angiogenic Agent
  • Antiangiogenesis Agent
  • Antineoplastic Agents
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Names and Synonyms

Name of Substance

  • Motesanib [USAN:INN]

Synonyms

  • AMG 706
  • AMG706
  • Motesanib
  • N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-((pyridin-4-ylmethyl)amino)pyridine-3-carboxamide
  • UNII-U1JK633AYI

Systematic Name

  • 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-

Registry Numbers

CAS Registry Number

  • 453562-69-1

FDA UNII

  • U1JK633AYI

Other Registry Number

  • 894356-47-9

System Generated Number

  • 0453562691

Structure Descriptors

InChI

1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)

InChIKey

RAHBGWKEPAQNFF-UHFFFAOYSA-N

Smiles

CC1(CNc2c1ccc(c2)NC(=O)c3cccnc3NCc4ccncc4)C