Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Eucalyptol [USAN:USP]
RN: 470-82-6
UNII: RV6J6604TK
InChIKey: WEEGYLXZBRQIMU-WAAGHKOSSA-N

Note

  • Solvent for gutta-percha; main constituent of oil of Eucalyptus (ingalipt).

Molecular Formula

  • C10-H18-O

Molecular Weight

  • 154.2512
 

Classification Codes

  • Anti-Infective Agents
  • Mutation Data
  • Reproductive Effect
  • Solvents

Names and Synonyms

Name of Substance

  • 1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octane
  • Cajeputol
  • Cineole
  • Eucalyptol
  • Eucalyptol [USAN:USP]

Synonyms

  • 1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octane
  • 1,8-Cineol
  • 1,8-Cineole
  • 1,8-Epoxy-p-menthane
  • 1,8-Oxido-p-menthane
  • 2-Oxa-1,3,3-trimethylbicyclo(2.2.2)octane
  • 2-Oxabicyclo(2.2.2)octane, 1,3,3-trimethyl-
  • AI3-00578
  • Cajeputol
  • CCRIS 3727
  • Cineole
  • Cineole (VAN)
  • EC 207-431-5
  • EINECS 207-431-5
  • Eucalyptol
  • Eucalyptol (natural)
  • Eucalyptole
  • Eucapur
  • Eukalyptol
  • Eukalyptol [Czech]
  • FEMA No. 2465
  • HSDB 991
  • NCI-C56575
  • NSC 6171
  • p-Cineole
  • p-Menthane, 1,8-epoxy-
  • Soledum
  • Terpan
  • UNII-RV6J6604TK
  • Zineol

Systematic Names

  • 1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octane
  • 1,8-Cineole
  • 1,8-Epoxy-p-menthane
  • 2-Oxabicyclo(2.2.2)octane, 1,3,3-trimethyl-
  • Cineole
  • p-Menthane, 1,8-epoxy-

Superlist Name

  • Eucalyptol

Registry Numbers

CAS Registry Number

  • 470-82-6

FDA UNII

  • RV6J6604TK

Other Registry Numbers

  • 10458-11-4
  • 8024-52-0
  • 8024-53-1
  • 855347-23-8

System Generated Number

  • 0000470826

Structure Descriptors

InChI

1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+

InChIKey

WEEGYLXZBRQIMU-WAAGHKOSSA-N

Smiles

C[C@@]12CC[C@@H](CC1)C(C)(C)O2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo subcutaneous 1500mg/kg (1500mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Trudy Instituta Fiziologii, Akademiya Nauk Kazakhshoi SSR. Transactions of the Institute of Physiology, Academy of Sciences of the Kazakh. SSR. Vol. 1, Pg. 134, 1955.
guinea pig LDLo intramuscular 2250mg/kg (2250mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Trudy Instituta Fiziologii, Akademiya Nauk Kazakhshoi SSR. Transactions of the Institute of Physiology, Academy of Sciences of the Kazakh. SSR. Vol. 1, Pg. 134, 1955.
mouse LD50 intramuscular 1gm/kg (1000mg/kg)   Journal of Scientific and Industrial Research, Section C: Biological Sciences. Vol. 21, Pg. 342, 1962.
mouse LD50 subcutaneous 1070mg/kg (1070mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Sapporo Igaku Zasshi. Sapporo Medical Journal. Vol. 3, Pg. 73, 1952.
rat LD50 oral 2480mg/kg (2480mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 1.5 deg C   EXP
Boiling Point 176.4 deg C   EXP
log P (octanol-water) 2.74 (none)   EXP
Water Solubility 3500 mg/L 21 EXP
Vapor Pressure 1.9 mm Hg 25 EXP
Henry's Law Constant 1.10E-04 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.11E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.