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Substance Name: Chlorfenvinphos [BSI:ISO]
RN: 470-90-6
UNII: F2G9XS1W91
InChIKey: FSAVDKDHPDSCTO-WQLSENKSSA-N

Note

  • An organophosphorus cholinesterase inhibitor that is used as an insecticide and an acaricide.

Molecular Formula

  • C12-H14-Cl3-O4-P

Molecular Weight

  • 359.5716
 

Classification Codes

Classification Codes

  • Acaricide
  • Acaricides
  • Agricultural Chemical
  • Cholinergic Agents
  • Cholinesterase Inhibitors
  • Enzyme Inhibitors
  • Human Data
  • Insecticide
  • Insecticides
  • Mutation Data
  • Neurotransmitter Agents
  • Out-Dated Pesticide
  • Pesticides

Superlist Classification Code

  • Threshold Planning Quantity (TPQ) = 500 lb
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Names and Synonyms

Results Name

  • Chlorfenvinphos [BSI:ISO]

Name of Substance

  • Chlorfenvinphos
  • Chlorfenvinphos [BSI:ISO]
  • Chlorofenvinphos
  • Clofenvinfos [INN:BAN]
  • Clorfenvinfos [INN]

MeSH Heading

  • Chlorfenvinphos

Synonyms

  • 2,4-Dichloro-alpha-(chloromethylene)benzyl alcohol diethyl phosphate
  • 2,4-Dichloro-alpha-(chloromethylene)benzyldiethyl phosphate
  • 2-Chloro-1-(2,4-dichlorophenyl)-ethenyl diethyl phosphate
  • 2-Chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate
  • 2-Chloro-1-(2,4-dichlorophenyl)vinyldiethylphosphate
  • AI3-24969
  • Apachlor
  • Benzyl alcohol, 2,4-dichloro-alpha-(chloromethylene)-, diethyl phosphate
  • beta-2-Chloro-1-(2',4'-dichlorophenyl) vinyl diethylphosphate
  • Birlan
  • Birlane
  • Birlane 10G
  • BRN 2338385
  • C 8949
  • C8949
  • Caswell No. 187
  • CCRIS 2701
  • CFV
  • CGA 26351
  • Chlofenvinphos
  • Chlorfehwinfos
  • Chlorfehwinfos [Polish]
  • Chlorfenvinfos
  • Chlorfenvinphos
  • Chlorphenvinfos
  • Chlorphenvinphos
  • Clofenvinfos
  • Clofenvinfoso
  • Clofenvinfoso [INN-Spanish]
  • Clofenvinfosum
  • Clofenvinfosum [INN-Latin]
  • Clorfenvinfos
  • Compound 4072
  • CVP (pesticide)
  • Dermaton
  • Diethyl 1-(2,4-dichlorophenyl)-2-chlorovinyl phosphate
  • Diethyl-1-(2,4-dichlorophenyl)-2-chlorovinyl phosphate
  • Diethyl-2-chloro-1-(2,4-dichlorophenyl)vinyl phosphate
  • EINECS 207-432-0
  • Enolofos
  • ENT 24969
  • EPA Pesticide Chemical Code 084101
  • GC 4072
  • Haptarax
  • Haptasol
  • HSDB 1540
  • O,O-Diaethyl-O-1-(4,5-dichlorphenyl)-2-chlor-vinyl-phosphat
  • O,O-Diaethyl-O-1-(4,5-dichlorphenyl)-2-chlor-vinyl-phosphat [German]
  • O,O-Diethyl O-(2-chloro-1-(2',4'-dichlorophenyl)vinyl) phosphate
  • O,O-Diethyl-O-1-(2',4'-dichlorophenyl)-2-chlorovinylphosphate
  • O,O-Dwuetylo-O-1-(2,4-dwuchlorofenylo)-2-chlorowinylofosforan
  • O,O-Dwuetylo-O-1-(2,4-dwuchlorofenylo)-2-chlorowinylofosforan [Polish]
  • O-2-Chloor-1-(2,4-dichloor-fenyl)-vinyl-O,O-diethylfosfaat
  • O-2-Chloor-1-(2,4-dichloor-fenyl)-vinyl-O,O-diethylfosfaat [Dutch]
  • O-2-Chlor-1-(2,4-dichlor-phenyl)-vinyl-O,O-diaethylphosphat
  • O-2-Chlor-1-(2,4-dichlor-phenyl)-vinyl-O,O-diaethylphosphat [German]
  • O-2-Cloro-1-(2,4-dicloro-fenil)-vinil-O,O-dietilfosfato
  • O-2-Cloro-1-(2,4-dicloro-fenil)-vinil-O,O-dietilfosfato [Italian]
  • OMS 1328
  • Phosphate de O,O-diethyle et de O-2-chloro-1-(2,4-dichlorophenyl) vinyle
  • Phosphate de O,O-diethyle et de O-2-chloro-1-(2,4-dichlorophenyl) vinyle [French]
  • Phosphoric acid, 2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl ester
  • Phosphoric acid, 2-chloro-1-(2,4-dichlorophenyl)vinyl diethyl ester
  • Sapecron
  • SD 4072
  • SD 7859
  • Shell 4072
  • Steladone
  • Supona
  • Tarene
  • UNII-F2G9XS1W91
  • Unitox
  • Vinylphate
  • Vinyphate
  • Zaprawa enolofos

Systematic Names

  • 2-Chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate
  • Chlorfenvinphos
  • Phosphoric acid, 2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl ester
  • Phosphoric acid, 2-chloro-1-(2,4-dichlorophenyl)vinyl diethyl ester

Superlist Names

  • 2-Chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate
  • Chlorfenvinfos
  • Chlorfenvinphos
  • Phosphoric acid, 2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl ester

Registry Numbers

CAS Registry Number

  • 470-90-6

FDA UNII

  • F2G9XS1W91

System Generated Number

  • 0000470906

Structure Descriptors

InChI

1S/C12H14Cl3O4P/c1-3-17-20(16,18-4-2)19-12(8-13)10-6-5-9(14)7-11(10)15/h5-8H,3-4H2,1-2H3/b12-8-

InChIKey

FSAVDKDHPDSCTO-WQLSENKSSA-N

Smiles

CCOP(=O)(OCC)O\C(=C/Cl)\c1ccc(Cl)cc1Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 13mg/kg (13mg/kg)   Journal de Toxicologie Clinique et Experimentale. Vol. 6(3), Pg. 175, 1986.
cattle LD50 oral 20mg/kg (20mg/kg)   Veterinary Record. Vol. 77, Pg. 1140, 1965.
chicken LD50 intraperitoneal 23100ug/kg (23.1mg/kg)   Veterinary Record. Vol. 77, Pg. 1140, 1965.
chicken LD50 oral 29100ug/kg (29.1mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
dog LD50 intravenous 51mg/kg (51mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Toxicology and Applied Pharmacology. Vol. 17, Pg. 323, 1970.
dog LD50 oral 1200mg/kg (1200mg/kg)   "Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R., Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971Vol. -, Pg. 18, 1971.
domestic animals - goat/sheep LD50 oral 71250ug/kg (71.25mg/kg)   Veterinary Record. Vol. 77, Pg. 1140, 1965.
guinea pig LD50 oral 125mg/kg (125mg/kg)   Biochemical Pharmacology. Vol. 16, Pg. 949, 1967.
human TDLo skin 10mg/kg (10mg/kg) BLOOD: OTHER CHANGES Industrial Medicine and Surgery. Vol. 38, Pg. 25, 1969.
mammal (species unspecified) LD50 oral 10mg/kg (10mg/kg)   Herba Polonica. Vol. 21, Pg. 53, 1975.
mouse LD50 intraperitoneal 87mg/kg (87mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967.
mouse LD50 intravenous 87mg/kg (87mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967.
mouse LD50 oral 65mg/kg (65mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 78, 1967.
mouse LD50 skin 336mg/kg (336mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 78, 1967.
mouse LD50 subcutaneous 339mg/kg (339mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967.
pigeon LD50 oral 13300ug/kg (13.3mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 148mg/kg (148mg/kg) PERIPHERAL NERVE AND SENSATION: FASCICULATIONS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Pesticide Science. Vol. 2, Pg. 148, 1971.
rabbit LD50 oral 300mg/kg (300mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Toxicology and Applied Pharmacology. Vol. 17, Pg. 323, 1970.
rabbit LD50 skin 400mg/kg (400mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 17, Pg. 323, 1970.
rat LC50 inhalation 50mg/m3/4H (50mg/m3)   Pesticide Manual. Vol. 9, Pg. 142, 1991.
rat LD50 intraperitoneal 8500ug/kg (8.5mg/kg)   Veterinary Record. Vol. 77, Pg. 1140, 1965.
rat LD50 intravenous 6600ug/kg (6.6mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Toxicology and Applied Pharmacology. Vol. 17, Pg. 323, 1970.
rat LD50 oral 10mg/kg (10mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C69, 1991.
rat LD50 skin 26400ug/kg (26.4mg/kg)   Acta Physiologica Polonica. Vol. 32, Pg. 507, 1981.
rat LD50 subcutaneous 7mg/kg (7mg/kg)   Acta Physiologica Polonica. Vol. 32, Pg. 507, 1981.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -2.00E+01 deg C   EXP
log P (octanol-water) 3.81 (none)   EXP
Water Solubility 124 mg/L 20 EXP
Vapor Pressure 7.50E-06 mm Hg 25 EXP
Henry's Law Constant 2.89E-08 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 5.78E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.