Substance Name: Golimumab [USAN:INN:BAN]
RN: 476181-74-5
UNII: 91X1KLU43E
Note
- Golimumab plus MTX effectively reduces the signs and symptoms of RA and is generally well tolerated in patients with an inadequate response to MTX.
Molecular Formula
- C6530-H10068-N1752-O2026-S44
Classification Codes
- Anti-Inflammatory Agents
- Immunologic Factors
- Immunosuppressive Agents
- Rheumatoid Arthritis, Uveitis, Asthma and Crohn's Disease
- Treatment of Inflammatory Disorders
- Treatment of Inflammatory Disorders; Rheumatoid Arthritis, Uveitis, Asthma and Crohn's Disease
- Tumor Necrosis Factor Inhibitors
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Golimumab
- Golimumab [USAN:INN:BAN]
Synonyms
- CNTO 148
- CNTO-148
- CNTO148
- Golimumab
- Golimumab (genetical recombination)
- HSDB 7852
- Simponi
- UNII-91X1KLU43E
Systematic Name
- Immunoglobulin G1, anti-(human tumor necrosis factor alpha) (human monoclonal CNTO 148 gamma1-chain), disulfide with human monoclonal CNTO 148 kappa-chain, dimer. Molecular weight is approximately 147,000 daltons
Mixture Name
- Simponi Aria
Registry Numbers
CAS Registry Number
- 476181-74-5
FDA UNII
- 91X1KLU43E
System Generated Number
- 0476181745