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Substance Name: Golimumab [USAN:INN:BAN]
RN: 476181-74-5


  • Golimumab plus MTX effectively reduces the signs and symptoms of RA and is generally well tolerated in patients with an inadequate response to MTX.

Molecular Formula

  • C6530-H10068-N1752-O2026-S44

Classification Codes

  • Anti-Inflammatory Agents
  • Immunologic Factors
  • Immunosuppressive Agents
  • Rheumatoid Arthritis, Uveitis, Asthma and Crohn's Disease
  • Treatment of Inflammatory Disorders
  • Treatment of Inflammatory Disorders; Rheumatoid Arthritis, Uveitis, Asthma and Crohn's Disease
  • Tumor Necrosis Factor Inhibitors

Names and Synonyms

Name of Substance

  • Golimumab
  • Golimumab [USAN:INN:BAN]


  • CNTO 148
  • CNTO-148
  • CNTO148
  • Golimumab
  • Golimumab (genetical recombination)
  • HSDB 7852
  • Simponi
  • UNII-91X1KLU43E

Systematic Name

  • Immunoglobulin G1, anti-(human tumor necrosis factor alpha) (human monoclonal CNTO 148 gamma1-chain), disulfide with human monoclonal CNTO 148 kappa-chain, dimer. Molecular weight is approximately 147,000 daltons

Mixture Name

  • Simponi Aria

Registry Numbers

CAS Registry Number

  • 476181-74-5


  • 91X1KLU43E

System Generated Number

  • 0476181745