Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Clorotepine maleate
RN: 4789-68-8
UNII: M5Z1H0WN1S
InChIKey: GWKBZIADWSOIQV-BTJKTKAUSA-N

Note

  • Major tranquilizer with action similar to those of the phenothiazines; used in schizophrenic & manic psychoses.

Molecular Formula

  • C19-H21-Cl-N2-S.C4-H4-O4

Molecular Weight

  • 460.9795
 

Classification Code

  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Clorotepine maleate

Name of Substance

  • Clorotepine maleate

Synonyms

  • 8-Chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin maleate
  • d,l-8-Chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin maleate
  • Octoclothepine maleate
  • UNII-M5Z1H0WN1S
  • VUFB-6281

Systematic Name

  • Piperazine, 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methyl-, maleate

Registry Numbers

CAS Registry Number

  • 4789-68-8

FDA UNII

  • M5Z1H0WN1S

Related Registry Number

  • 13448-22-1 (Parent)

System Generated Number

  • 0004789688

Molecular Formulas

Molecular Formula

  • C19-H21-Cl-N2-S.C4-H4-O4

Molecular Formula Fragments

  • C19-H21-Cl-N2-S
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C19H21ClN2S.C4H4O4/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19;5-3(6)1-2-4(7)8/h2-7,13,17H,8-12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChIKey

GWKBZIADWSOIQV-BTJKTKAUSA-N

Smiles

CN1CCN(CC1)C2Cc3ccccc3Sc4c2cc(cc4)Cl.C(=C\C(=O)O)\C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 46300ug/kg (46.3mg/kg)   Collection of Czechoslovak Chemical Communications. Vol. 33, Pg. 1831, 1968.
mouse LD50 oral 104mg/kg (104mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
Collection of Czechoslovak Chemical Communications. Vol. 38, Pg. 2484, 1973.
rabbit LD50 oral 310mg/kg (310mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 84, 1972.