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Substance Name: Iboctadekin [USAN:INN]
RN: 479198-61-3
UNII: X08H9UZ7TO

Note

  • Purified iboctadekin is a recombinant human cytokine, interleukin-18 (IL-18) belonging to the IL-1 family, also known as interferon-gamma-inducing factor (IGIF), expressed in a non-pathenogenic strain of Escherichia coli. Iboctadekin, consisting of 157 amino acids, is formed in vivo following the activation of proIL-18 by caspase-4 and consists of a single polypeptide chain that is not glycosylated. The protein contains four cysteine residues present as free sulfhydryl groups

Molecular Formulas

  • C801-H1264-N212-O252-S10
  • Unspecified

Molecular Weight

  • 18216.6886
 

Classification Code

  • Treatment of Disseminated Solid Tumors
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Names and Synonyms

Name of Substance

  • Iboctadekin [USAN:INN]

Synonyms

  • Human recombinant Interleukin-18
  • Iboctadekin
  • Purified iboctadekin is a recombinant human cytokine, interleukin-18 (IL-18) belonging to the IL-1 family, also known as interferon-g-inducing factor (IGIF), expressed in a non-pathenogenic strain of Escherichia coli. Iboctadekin, consisting of 157 amino acids, is formed in vivo following the activation of proIL-18 by caspase-4 and consists of a single polypeptide chain that is not glycosylated. The protein contains four cysteine residues present as free sulfhydryl groups.
  • SB 485232
  • SB-485232
  • UNII-X08H9UZ7TO

Systematic Name

  • Human interleukin-18 (recombinant, expressed in Escherichia coli)

Registry Numbers

CAS Registry Number

  • 479198-61-3

FDA UNII

  • X08H9UZ7TO

System Generated Number

  • 0479198613