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Substance Name: Ninhydrin
RN: 485-47-2
UNII: HCL6S9K23A
InChIKey: FEMOMIGRRWSMCU-UHFFFAOYSA-N

Note

  • 2,2-Dihydroxy-1H-indene-1,3-(2H)-dione. Reagent toxic to skin and mucus membranes. It is used in chemical assay for peptide bonds, i.e., protein determinations and has radiosensitizing properties.

Molecular Formula

  • C9-H6-O4

Molecular Weight

  • 178.1424
 

Classification Codes

  • Agricultural Chemical
  • Experimental Pesticide
  • Indicators and Reagents
  • Radiation-Sensitizing Agents
  • Unspecified / Unclassified Pesticide

Names and Synonyms

Name of Substance

  • Ninhydrin

MeSH Heading

  • Ninhydrin

Synonyms

  • 1,2,3-Indantrione monohydrate
  • 1,2,3-Indantrione, 2-hydrate
  • 2,2-Dihydroxy-1,3-indandione
  • 2,2-Dihydroxy-1H-indene-1,3(2H)-dione
  • 4-07-00-02786 (Beilstein Handbook Reference)
  • AI3-04464
  • BRN 1910963
  • CCRIS 4849
  • EINECS 207-618-1
  • Ninhydrin
  • Ninhydrin hydrate
  • Triketohydrindene hydrate
  • UNII-HCL6S9K23A

Systematic Names

  • 1,3-Indandione, 2,2-dihydroxy-
  • 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-
  • Indan-1,2,3-trione
  • Ninhydrin

Registry Numbers

CAS Registry Number

  • 485-47-2

FDA UNII

  • HCL6S9K23A

System Generated Number

  • 0000485472

Structure Descriptors

InChI

1S/C9H6O4/c10-7-5-3-1-2-4-6(5)8(11)9(7,12)13/h1-4,12-13H

InChIKey

FEMOMIGRRWSMCU-UHFFFAOYSA-N

Smiles

c1ccc2c(c1)C(=O)C(C2=O)(O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 78mg/kg (78mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 151, Pg. 719, 1957.
rat LDLo oral 250mg/kg (250mg/kg)   National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 28, 1953.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 242 dec deg C   EXP
log P (octanol-water) 0.67 (none)   EXP
Water Solubility 1.51E+04 mg/L 25 EST
Vapor Pressure 2.36E-07 mm Hg 25 EST
Henry's Law Constant 3.38E-11 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.03E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.