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Substance Name: Sitagliptin [INN:BAN]
RN: 486460-32-6
UNII: QFP0P1DV7Z
InChIKey: MFFMDFFZMYYVKS-SECBINFHSA-N

Note

  • MK-0431 is the phosphate salt of the (2R)-isomer; inhibitor of DPP4 protein resulting in enhanced level of Glucagon-Like Peptide 1.

Molecular Formula

  • C16-H15-F6-N5-O

Molecular Weight

  • 407.3165
 

Classification Codes

  • Dipeptidyl-Peptidase IV Inhibitors
  • Enzyme Inhibitors
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Hypoglycemic Agents
  • Incretins
  • Protease Inhibitors

Names and Synonyms

Name of Substance

  • Sitagliptin
  • Sitagliptin [INN:BAN]

Synonyms

  • EC 690-730-1
  • HSDB 7516
  • Januvia
  • LEZ 763
  • LEZ763
  • Sitagliptin
  • Tesavel
  • UNII-QFP0P1DV7Z
  • Xelevia

Systematic Names

  • 1,2,4-Triazolo(4,3-a)pyrazine, 7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8-tetrahydor-3-(trifluoromethyl)-
  • 7-((3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)buyl)-5,6,7,8-tetrahydro-3-trifluoromethyl)-1,4-triazolo(4,3-a)

Mixture Name

  • Janumet

Registry Numbers

CAS Registry Number

  • 486460-32-6

FDA UNII

  • QFP0P1DV7Z

System Generated Number

  • 0486460326

Structure Descriptors

InChI

1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1

InChIKey

MFFMDFFZMYYVKS-SECBINFHSA-N

Smiles

c1(c(F)cc(c(F)c1)C[C@H](CC(N1CCn2c(C1)nnc2C(F)(F)F)=O)N)F