Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tetrahydropalmatine hydrochloride
RN: 4880-82-4
UNII: RH72T8K75E
InChIKey: MGSZZQQRTPWMEI-LMOVPXPDSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C21-H25-N-O4.Cl-H

Molecular Weight

  • 391.8924
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Tetrahydropalmatine hydrochloride

Synonyms

  • 1-Tetrahydropalmitine HCl
  • 2,3,9,10-Tetramethoxy-13a-alpha-berbine hydrochloride
  • 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, hydrochloride, (S)-
  • Gindarin hydrochloride
  • Gindarine hydrochloride
  • l-Tetrahydropalmitine, hydrochloride
  • NSC 36363
  • Tetrahydropalmatine hydrochloride
  • UNII-RH72T8K75E

Systematic Names

  • 13a-alpha-Berbine, 2,3,9,10-tetramethoxy-, hydrochloride
  • 13aalpha-Berbine, 2,3,9,10-tetramethoxy-, hydrochloride (8CI)
  • 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, hydrochloride, (S)- (9CI)

Registry Numbers

CAS Registry Number

  • 4880-82-4

FDA UNII

  • RH72T8K75E

System Generated Number

  • 0004880824

Molecular Formulas

Molecular Formula

  • C21-H25-N-O4.Cl-H

Molecular Formula Fragments

  • C21-H25-N-O4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C21H25NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,10-11,17H,7-9,12H2,1-4H3;1H/t17-;/m0./s1

InChIKey

MGSZZQQRTPWMEI-LMOVPXPDSA-N

Smiles

Cl.COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(OC)c4OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 460mg/kg (460mg/kg)   Farmakologiya i Toksikologiya Vol. 46(4), Pg. 107, 1983.
mouse LD50 intraperitoneal 550mg/kg (550mg/kg)   Indian Journal of Medical Research. Vol. 60, Pg. 472, 1972.
mouse LD50 oral 1190mg/kg (1190mg/kg)   Farmakologiya i Toksikologiya Vol. 46(4), Pg. 107, 1983.
rat LD50 intraperitoneal 330mg/kg (330mg/kg)   Farmakologiya i Toksikologiya Vol. 46(4), Pg. 107, 1983.
rat LD50 oral 580mg/kg (580mg/kg)   Farmakologiya i Toksikologiya Vol. 46(4), Pg. 107, 1983.