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Substance Name: Acridine Orange
RN: 494-38-2
UNII: F30N4O6XVV
InChIKey: DPKHZNPWBDQZCN-UHFFFAOYSA-N

Note

  • A cationic cytochemical stain specific for cell nuclei, especially DNA. It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms.

Molecular Formula

  • C17-H19-N3

Molecular Weight

  • 265.3581
 

Classification Codes

Classification Codes

  • Coloring Agents
  • Drug / Therapeutic Agent
  • Fluorescent Dyes
  • Indicators and Reagents
  • Luminescent Agents
  • Mutagens
  • Mutation Data
  • Noxae
  • Tumor Data

Superlist Classification Code

  • Overall Carcinogenic Evaluation: Group 3
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Names and Synonyms

Name of Substance

  • Acridine Orange

MeSH Heading

  • Acridine Orange

Synonyms

  • 2,8-Bisdimethylaminoacridine
  • 3,6-Bis(dimethylamino)acridine
  • 3,6-Bis-(dimethylamino)akridin
  • 3,6-Bis-(dimethylamino)akridin [Czech]
  • 3,6-Di(dimethylamino)acridine
  • 4-22-00-05490 (Beilstein Handbook Reference)
  • Acridine Orange Base
  • Acridine Orange Free Base
  • Brilliant Acridine Orange E
  • BRN 0020916
  • C.I. 46005B
  • C.I. No. 46005:1
  • C.I. Solvent Orange 15
  • N,N,N',N'-Tetramethyl-3,6-acridinediamine
  • N,N,N',N'-Tetramethylacridinediamine
  • N,N,N(sup 1),N(sup 1)-Tetramethylacridinediamine
  • NSC 194350
  • Oranz akridinova
  • Oranz akridinova [Czech]
  • Oranz rozpoustedlova 15
  • Oranz rozpoustedlova 15 [Czech]
  • Solvent Orange 15
  • UNII-F30N4O6XVV
  • Waxoline Orange A

Systematic Names

  • 3,6-Acridinediamine, N,N,N',N'-tetramethyl- (9CI)
  • Acridine, 3,6-bis(dimethylamino)-
  • Acridinediamine, N,N,N',N'-tetramethyl- (9CI)

Superlist Name

  • Acridine Orange

Registry Numbers

CAS Registry Number

  • 494-38-2

FDA UNII

  • F30N4O6XVV

Related Registry Number

  • 65-61-2 (Parent)

System Generated Number

  • 0000494382

Structure Descriptors

InChI

1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3

InChIKey

DPKHZNPWBDQZCN-UHFFFAOYSA-N

Smiles

c12c(cc3ccc(cc3n1)N(C)C)ccc(c2)N(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 250mg/kg (250mg/kg)   British Journal of Experimental Pathology. Vol. 28, Pg. 1, 1947.