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Substance Name: Anabasine
RN: 494-52-0
UNII: LMS11II2LO
InChIKey: MTXSIJUGVMTTMU-JTQLQIEISA-N
Note
- A piperidine botanical insecticide.
Molecular Formula
- C10-H14-N2
Molecular Weight
- 162.2346
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Agricultural Chemical
- Drug / Therapeutic Agent
- Insecticide
- Insecticides
- Out-Dated Pesticide
- Pesticides
- Reproductive Effect
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Names and Synonyms
Name of Substance
- Anabasine
MeSH Heading
- Anabasine
Synonyms
- (-)-2-(3'-Pyridyl)piperidine
- (S)-3-(2-Piperidinyl)pyridine
- 2-(3'-Pyridyl) piperidine
- 3-(2-Piperidinyl)pyridine
- 5-23-06-00096 (Beilstein Handbook Reference)
- Anabasin
- Anabasine
- Anabazin
- BRN 0082637
- Caswell No. 051
- EINECS 207-791-3
- EPA Pesticide Chemical Code 006001
- HSDB 3462
- L-3-(2'-Piperidyl)pyridine
- Neonicotine
- Neonikotin
- NSC 87504
- Piperidine, 2-(3-pyridyl)-
- Pyridine, 3-(2-piperidinyl)-, (S)-
- Pyridine, 3-(2-piperidyl)-
- Pyridine, 3-(2-pyridyl) piperidine
- S-(-)-Anabasine
- UNII-LMS11II2LO
Systematic Names
- Anabasine
- Piperidine, 2-(3-pyridyl)- (8CI)
- Pyridine, 3-(2-piperidinyl)-, (S)- (9CI)
- Pyridine, 3-(2S)-2-piperidinyl-
Registry Numbers
CAS Registry Number
- 494-52-0
FDA UNII
- LMS11II2LO
System Generated Number
- 0000494520
Structure Descriptors
InChI
InChI=1S/C10H14N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8,10,12H,1-2,5,7H2/t10-/m0/s1InChIKey
MTXSIJUGVMTTMU-JTQLQIEISA-NSmiles
C1CC[C@H](NC1)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | intravenous | 3mg/kg (3mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 48, Pg. 95, 1933. |
| dog | LDLo | oral | 50mg/kg (50mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 48, Pg. 95, 1933. |
| guinea pig | LD50 | subcutaneous | 22mg/kg (22mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1348, 1986. | |
| guinea pig | LDLo | skin | 100mg/kg (100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 48, Pg. 95, 1933. |
| mammal (species unspecified) | LD50 | unreported | 39mg/kg (39mg/kg) | Pharmaceutical Chemistry Journal Vol. 10, Pg. 1478, 1976. | |
| mouse | LD50 | intravenous | 1620ug/kg (1.62mg/kg) | "Toxic Plants and Other Natural Toxicants, Proceedings of the International Symposium on Poisonous Plants, 5th, San Angelo, Texas 1997" Garland, T., and C. Barr eds. New York, CABI Publishing 1998Vol. -, Pg. 345, 1998. | |
| rabbit | LDLo | intravenous | 1mg/kg (1mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 48, Pg. 95, 1933. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 9 | deg C | EXP | |
| Boiling Point | 276 | deg C | EXP | |
| pKa Dissociation Constant | 11 | (none) | 30 | EXP |
| log P (octanol-water) | 0.97 | (none) | EXP | |
| Water Solubility | 1.00E+06 | mg/L | 25 | EXP |
| Vapor Pressure | 3.01E-03 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.81E-09 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 1.01E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.